A case-control study of dietary behavior and central precocious puberty among children
Objective To explore the relationship between dietary behavior,dietary frequency and central precocious puberty(CPP)among children in Wuhan,so as to provide a scientific basis for elucidating the possible and related dietary factors leading to precocious puberty.Methods From February to December 2023,100 children with CPP and 100 healthy children were collect-ed in Wuhan Children's Hospital for a case-control study.Questionnaires and interviews were used to collect demographic informa-tion,child lifestyle,as well as dietary behavior and dietary frequency in the past six months.Conditional Logistic regression model was used to analyze the relationship of children's dietary behavior and dietary frequency with CPP.Results No associations were found between three dietary behavior,including emotional eating,restrictive eating,and external eating,with CPP at baseline(P＞0.05).In the association analysis of dietary frequency and CPP,the risk of CPP was higher in those who consumed red meat＞5 times/week(OR=1.93,95％CI=1.01-3.68),carbonated beverages ≥4 times/month(OR=2.70,95％CI=1.03-7.08),fruit juices ≥4 times/month(OR=2.31,95％CI=1.02-5.25),and nutritional supplementation(OR=2.77,95％CI=1.47-5.22),whereas the risk of CPP was lower in those who consumed nuts ≥4 times/month(OR=0.21,95％CI=0.08-0.57)(P＜0.05).Conclusion Consumption of higher amounts of red meat,high frequency of carbonated and juice-based sugary drinks,and nutrient supplementation may be contributing factors to the development of CPP,whereas regular consumption of nuts is less likely to be as-sociated with the development of CPP.
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