Research advances in thermal ablation for lung cancer
Although surgical resection remains to be the best treatment strategy for stage Ⅰ non-small cell lung cancer(NSCLC),percutaneous thermal ablation offers an important option for patients who are unable to undergo surgical resection.Currently,there are three main thermal ablation methods used in the treatment of lung cancer,including radiofrequency ablation(RFA),microwave ablation(MWA)and argon-helium cryoablation(AHC).With the improvement of technique and the accumulation of experience in the treatment of lung cancer,some limitations are disclosed in the initial application of RFA,such as heat sink effect,skin burns and rapid carbonization.These shortcomings have been overcome in the development of MWA and AHC.The feasibility and safety of thermal ablation for the treatment of lung cancer has been demonstrated and its efficacy has been significantly improved(especially for the tumour diameter≤3 cm).This article will focus on the application and recent research developments of these ablation techniques in the treatment of lung cancer.
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