Effect of aortic valve neo-cuspidization in multiple valve repair surgery:A retrospective cohort study in a single center
Objective To explore the effect of aortic valve neo-cuspidization(AVNeo)for patients with severe aortic valve lesions simultaneously.Methods Patients who underwent AVNeo combined valve repair surgery for multiple valve diseases were included in Beijing Anzhen Hospital from May 2016 to September 2023.Results We included 11 patients with 7 males and 4 females at a median age of 38(36,49)years.Rheumatic heart disease was found in 5(45.5％)patients and non-rheumatic heart disease in 6(54.5％)patients.The median EuroSCORE Ⅱ score was 1.62(1.18,1.75)points.Eight patients underwent AVNeo plus mitral and tricuspid valve repair,and 3 patients underwent AVNeo plus mitral valve repair.The median operative time was 356(315,415)min,and the median cardiopulmonary bypass time and aortic clamping time were 203(174,231)min and 168(131,188)min,respectively.In the early stage,2 patients underwent combined valve repair surgery,and 1 patient underwent in-hospital reoperation for aortic valve replacement because of severe aortic regurgitation.There were 9 patients in the mature stage of AVNeo,and no perioperative adverse events or moderate or above residual valvular disease occurred.All patients recovered and were discharged from the hospital.The follow-up period was 3-99 months,and no reoperation,severe valve disease,bleeding,cerebral infarction,or other adverse events occurred in all patients.Conclusion For non-elderly patients whose mitral and tricuspid valves can be repaired successfully with severe aortic valve lesions,AVNeo can be attempted after proficiency.But the operation time and cardiopulmonary bypass time will inevitably be prolonged,and the patient's basic situation should be carefully evaluated before surgery.
Aortic valve neo-cuspidizationmultiple valve repairretrospective cohort study
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