Clinical and CT findings of 25 patients with bronchiolar adenoma
Objective To study the clinical and CT findings of bronchiolar adenoma.Methods Patients diagnosed with bronchiolar adenoma confirmed by surgical pathology at Linyi People's Hospital and Yantai Yuhuangding Hospital from 2016 to 2021 were collected.Their clinical and CT imaging features were retrospectively analyzed.Results Finally,25 patients were collected,including 6 males and 19 females,aged 32-73(58.6±10.1)years.The immunohistochemical Ki-67(MIB1)of all lesions was＜5％.The lesions were located in the upper and middle lobe of both lungs in 9 patients,lower lobes in 16 patients,extrapulmonary zone in 22 patients,intrapulmonary middle zone in 3 patients,round in 11 patients,irregular in 14 patients,well-defined in 22 patients,pure ground-glass/mixed ground-glass nodules in 6 patients,solid nodules in 19 patients.There were 11 patients with central small cavity,18 patients with single bronchioles sign,19 patients without adhesion with adjacent pleura,and 24 patients without mediastinal lymph node enlargement.Conclusion Bronchiolar adenomas usually occur in the middle-aged and elderly,mostly in the lower lobe of both lungs and the distribution of the peripheral lung field,most of the patients do not have any clinical symptoms,and the postoperative prognosis is good.CT may show large nodules or masses,pure ground-glass/mixed ground-glass nodules,irregular solid nodules and central small cavities.Irregular stellate nodules,central small cavity shadow,and single bronchiolar vascular bundle connected with the lesions are relatively specific imaging findings of bronchiolar adenoma.
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