Risk factors for death after one-stage radical surgery in children with interruption of aortic arch and ventricular septal defect
Objective To analyze the risk factors for death in children with interruption of aortic arch(IAA)and ventricular septal defect(VSD)after one-stage radical surgery.Methods A retrospective analysis was performed on patients with IAA and VSD who underwent one-stage radical treatment in the First Hospital of Hebei Medical University from January 2006 to January 2017.Cox proportional hazards regression model was used to analyze the risk factors for death after the surgery.Results A total of 152 children were enrolled,including 70 males and 82 females.Twenty-two patients died with a mean age of 30.73±9.21 d,and the other 130 patients survived with a mean age of 37.62±11.06 d.The Cox analysis showed that younger age(OR=0.551,95％CI 0.320-0.984,P=0.004),low body weight(OR=0.632,95％CI 0.313-0.966,P=0.003),large ratio of VSD diameter/aortic root diameter(VSD/AO,OR=2.547,95％CI 1.095-7.517,P=0.044),long cardiopulmonary bypass time(OR=1.374,95％CI 1.000-3.227,P=0.038),left ventricular outflow tract obstruction(LVOTO,OR=3.959,95％CI 1.123-9.268,P=0.015)were independent risk factors for postoperative death.Conclusion For children with IAA and VSD,younger age,low body weight,large ratio of VSD/AO,long cardio-pulmonary bypass time and LVOTO are risk factors for death after one-stage radical surgery.
万方数据
维普
