首页|单纯超声引导下经皮二尖瓣球囊扩张术治疗妊娠期中重度二尖瓣狭窄的临床疗效

单纯超声引导下经皮二尖瓣球囊扩张术治疗妊娠期中重度二尖瓣狭窄的临床疗效

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目的 探讨单纯超声引导下经皮二尖瓣球囊扩张术治疗妊娠期中重度二尖瓣狭窄患者的效果.方法 纳入2018年8月-2022年6月于阜外医院明确诊断为中重度二尖瓣狭窄并接受单纯超声引导下经皮二尖瓣球囊扩张术治疗的妊娠期患者,对其基线资料、手术情况、超声心动图结果和随访结果进行回顾性分析.结果 共纳入3例妊娠期患者,年龄30～35岁,孕周19～26周,纽约心脏协会(NYHA)心功能分级均为Ⅲ级.3例患者均成功完成手术,平均二尖瓣瓣口面积由术前0.9 cm2增加至术后2.1 cm2,平均跨瓣压差由术前15.0 mm Hg降至术后6.7 mm Hg,无围术期不良事件.术后随访3～48个月,3例患者均顺利完成分娩并恢复正常生活,母胎安全.结论 单纯超声引导下经皮二尖瓣球囊扩张术治疗妊娠期中重度二尖瓣狭窄患者安全有效,母胎结局满意.
Clinical efficacy of percutaneous balloon mitral valvuloplasty under echocardiographic guidance for moderate to severe mitral stenosis during pregnancy
Objective To investigate the effect of percutaneous balloon mitral valvuloplasty under echocardiographic guidance for patients with moderate to severe mitral stenosis during pregnancy.Methods A retrospective observational study was conducted to include pregnant women who were diagnosed with moderate to severe mitral stenosis and underwent percutaneous balloon mitral valvuloplasty under echocardiographic guidance in Fuwai Hospital from August 2018 to June 2022,and their baseline characteristics,surgical outcomes,echocardiographic results,and follow-up results were analyzed.Results A total of 3 pregnant women aged 30-35 years,with gestational age of 19-26 weeks,and New York Heart Association(NYHA)function class Ⅲ were included.All the procedures were successfully performed.The mitral valve orifice area increased from 0.9 cm2 preoperatively to 2.1 cm2 postoperatively.The mean transvalvular pressure gradient decreased from 15.0 mm Hg preoperatively to 6.7 mm Hg postoperatively.No perioperative adverse events occurred.The follow-up time ranged from 3 to 48 months.All patients delivered uneventfully and returned to normal life,with maternal-fetal safety.Conclusion Percutaneous balloon mitral valvuloplasty under echocardiographic guidance is a feasible and effective procedure for the treatment of patients with moderate to severe mitral stenosis in pregnancy,with satisfactory maternal-fetal outcomes.

Pregnancymitral stenosispercutaneous balloon mitral valvuloplastyechocardiography-guided intervention

魏培坚、李文超、李航、房芳、张凤文、欧阳文斌、李世国、张德元、林逸贤、潘湘斌

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中国医学科学院北京协和医学院国家心血管病中心阜外医院结构性心脏病中心(北京 100037)

国家卫生健康委员会心血管疾病再生医学研究重点实验室中国医学科学院心血管创新器械重点实验室国家心血管疾病临床医学研究中心(北京 100037)

先健科技(深圳)有限公司(广东深圳 518057)

香港嘉诺撒医院亚洲心脏科中心(香港 999077)

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妊娠 二尖瓣狭窄 经皮二尖瓣球囊扩张术 超声引导介入手术

中国医学科学院医学与健康科技创新工程国家重点研发计划国家重点研发计划中央高水平医院临床科研业务费专项中央高水平医院临床科研业务费专项国家重大科研仪器研制项目

2021-I2M-1-0652022YFC25034002023YFC24127052022-GSP-GG-182023-GSP-RC-0482327801

2024

10.7507/1007-4848.202302006

中国胸心血管外科临床杂志
四川大学华西医院

中国胸心血管外科临床杂志

CSTPCD北大核心
影响因子：0.846
ISSN：1007-4848
年,卷(期)：2024.31(9)
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