Application and development trends of population pharmacokinetic techniques in virtual clinical trials
Population pharmacokinetics is a research technique based on computer simulation and data analysis,and it has been employed to investigate the dynamic behavior of drug metabolism in different populations.This approach could address practical challenges such as prolonged clinical trial durations,high costs,and increased difficulty in traditional clinical trials.By comprehensively analyzing differences in the internal drug metabolism processes across populations with varying physiological and pathological conditions,population pharmacokinetics has emerged as an effective method to optimize drug development and clinical applications.This article provides a preliminary overview of the essence of population pharmacokinetics,its application in clinical trials,and potential future trends.We hope to serve as a reference and guidance for the application of new technologies and methods in clinical trials.
Population pharmacokineticsvirtual clinical trialsmodeling and simulation
万方数据
维普
