首页|1990-2019年中国青壮年主动脉瘤负担:基于2019年全球疾病负担数据库

1990-2019年中国青壮年主动脉瘤负担:基于2019年全球疾病负担数据库

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目的 探索我国青壮年主动脉瘤(aortic aneurysm,AA)的疾病负担,为公共卫生政策的制定提供参考.方法 分析1990-2019年全球疾病负担(Global Burden of Disease,GBD)数据库中国青壮年不同性别的AA死亡率和寿命损失年数(years of life lost,YLLs),并与全球及按社会人口学指数分层的青壮年AA数据进行对比.使用Joinpoint分析中国青壮年男、女AA负担的时间趋势.分析青壮年AA负担的归因风险因素,并探讨其特点.结果 在中国青壮年(15~39岁)中,2019年AA死亡总数为657例[95%UI(549,791)],较1990年上升16.90%o 2019年的死亡率为0.13/10万[95%UI(0.11,0.16)],较1990年上升30.00%.同时,2019年中国青壮年AA 共产生 36 921 YLLs[95%UI(30 865,44 445)],较 1990 年增长 13.21%.2019 年 YLLs 率为 7.42/10 万[95%UI(6.20,8.93)],较 1990 年增长 24.92%;其中男性 YLLs 率为 11.49/10 万[95%UI(9.22,14.28)],增长35.18%;女性为3.11/10万[95%UI(2.36,3.98)],下降3.12%.男性青壮年AA死亡率和YLLs率均高于女性,2019年较1990年的增长率亦明显高于女性.结论 1990-2019年中国青壮年AA疾病负担显著增加,以男性增加为主.中国青壮年AA男性和女性YLLs率时间趋势明显不一致.中国男性青壮年AA的YLLs率与经济发展和医疗技术水平进展呈正相关,正处于逐渐增长过程.中国女性青壮年YLLs率远低于全球平均水平,这与中国女性吸烟率低密切相关.
Aortic aneurysm burden among young adults in China from 1990 to 2019:Data from Global Burden of Disease 2019
Objective To provide reference for the formulation of public health policies through exploring the disease burden of aortic aneurysm(AA)in Chinese young adults.Methods We analyzed sex-specific mortality rates and years of life lost(YLLs)among Chinese young adults with AA in Global Burden of Disease(GBD)from 1990 to 2019,and compared with global and young adult AA data stratified by sociodemographic index(SDI).Joinpoint was used to analyze the time trend of AA burden among young males and females in China.The attributable risk factors for AA burden in young adults and its characteristics were analyzed.Results Among young adults(15-39 years old)in China,the total of AA deaths in 2019 was 657(95%UI 549-791),with an increase of 16.90%compared with 1990.The mortality rate in 2019 was 0.13 per 100 000(95%UI 0.11-0.16),with an increase of 30.00%compared with 1990.In 2019,a total of 36921 YLLs(95%UI 30 865-44 445)were produced by young adults in China,with an increase of 13.21%compared with 1990.The YLLs rate in 2019 was 7.42 per 100 000(95%UI 6.20-8.93),with an increase of 24.92%compared with 1990.The male YLLs rate was 11.49 per 100 000(95%UI 9.22-14.28),with an increase of 35.18%.The female YLLs rate was 3.11 per 100 000(95%UI 2.36-3.98),with a decrease of 3.12%.Both the AA mortality rate and YLLs rate in male young adults were higher than those in female young adults,and the growth rate from 1990 to 2019 was significantly higher than that in females.Conclusion The disease burden of AA among young adults in China increases significantly from 1990 to 2019,mainly among males.The time trend of male and female AA YLLs in Chinese young adults is obviously inconsistent.The AA YLLs of Chinese male young adults are positively correlated with economic development and the progress of medical technology,and are in the process of gradual increase.The AA YLLs of Chinese female young adults are much lower than the average level,which is closely related to the low smoking rate.

Aortic aneurysmyoung adultsdisease burden

刘林波、余皓、柳文韬、唐琦、施森

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绵阳市第三人民医院·四川省精神卫生中心血管外科(四川绵阳 621000)

西南医科大学附属医院血管外科(四川泸州 646099)

主动脉瘤 青壮年 疾病负担

2024

中国胸心血管外科临床杂志
四川大学华西医院

中国胸心血管外科临床杂志

CSTPCD北大核心
影响因子:0.846
ISSN:1007-4848
年,卷(期):2024.31(12)