Correlation between preoperative coronary angiography and postoperative acute kidney injury in cardiac surgery:A retrospective study in a single center
Objective To explore the relationship between preoperative coronary angiography and postoperative acute kidney injury(AKI)in cardiac surgery.Methods The clinical data of patients who underwent coronary angiography within 30 days before cardiac surgery in the First Affiliated Hospital of Xi'an Jiaotong University from January 2015 to April 2019 were retrospectively analyzed.Univariate analysis and multivariate logistic regression analyses were used to explore the relationship between the interval from preoperative coronary angiography to cardiac surgery and postoperative AKI.Results Finally 1 112 patients were collected,including 700 males and 412 females,with a median age of 61(55,66)years.The incidence of postoperative AKI was 40.8％(454/1 112),of which grade 2-3 AKI accounted for 11.9％.Multivariate analysis showed that age(OR=1.049,95％CI 1.022-1.077,P＜0.001),body mass index(OR=1.065,95％CI 1.010-1.123,P=0.020)and time interval between preoperative coronary angiography and cardiac surgery within 24 hours(OR=1.625,95％CI 1.116-2.364,P=0.011)were independent predictors of postoperative AKI.Patients who underwent coronary angiography within 24 hours before surgery had a 10.6％higher incidence of postoperative AKI compared to those who underwent angiography ≥24 hours before surgery(P=0.004).Patients who underwent valve surgery with or without coronary artery bypass grafting(CABG)had a higher risk of AKI than those who only underwent CABG.The in-hospital stay of patients who developed AKI was 2 days longer than those without AKI.However,undergoing coronary angiography within 24 hours before cardiac surgery did not prolong the length of ICU stay or hospital stay,nor did it increase the risk of death or renal failure after the operation.Conclusion Undergoing coronary angiography within 24 hours before cardiac surgery increases the risk of postoperative AKI.
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