Research progress of shear-thinning bioink in 3D bioprinting tissue trachea
Shear thinning is an ideal feature of bioink because it can reduce the chance of blocking.For extrusion based biological printing,bioink will experience shear force when passing through the biological printer.The shear rate will increase with the increase of extrusion rate,and the apparent viscosity of shear-thinning bioink will decrease,which makes it easier to block,thus achieving the structural fidelity of 3D printing tissue.The manufacturing of complex functional structures in tissue trachea requires the precise placement and coagulation of bioink layer by layer,and the shear-thinning bioink may well meet this requirement.This review focuses on the importance of mechanical properties,classification and preparation methods of shear-thinning bioink,and lists its current application status in 3D printing tissue trachea to discuss the more possibilities and prospects of this biological material in tissue trachea.
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