首页|儿童青少年抑郁症状的风险预测模型:一项基于NHIS数据的临床研究

儿童青少年抑郁症状的风险预测模型:一项基于NHIS数据的临床研究

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目的 探讨儿童青少年抑郁症状发生的主要危险因素,并构建列线图模型.方法 选取2022年美国健康访谈调查(NHIS)收集的符合条件的数据进行分析,数据主要包含儿童和家庭的人口学特征.采用LASSO分析进行儿童青少年抑郁症状的预测因素初步筛选,利用logistic回归进行多因素分析,最后用筛选的独立危险因素构建抑郁症状预测列线图.结果 有抑郁症状组的年龄为(12.7±3.3)岁,无抑郁症状组的年龄为(11.7±3.5)岁.Logistic回归分析显示,女性、年龄稍大、参加体育活动较少、被种族歧视、曾与有精神疾病或严重抑郁者同住、曾受过或目睹过暴力、曾患孤独症、曾患多动症、健康状况不良为儿童青少年抑郁症状发生的主要危险因素(P<0.05).儿童青少年抑郁症状的列线图模型的C-index为0.71;校正曲线的预测值和实际值基本吻合;模型的ROC曲线下面积为0.712.结论 性别、年龄、参加体育活动、种族歧视、曾与有精神疾病或严重抑郁者同住、曾受过或目睹过暴力、孤独症、多动症、健康状况是儿童青少年抑郁症状发生的主要影响因素,儿童青少年抑郁症状列线图预测模型的临床应用价值较高.
Risk prediction model for depressive symptoms in children and adoles-cents:A clinical study based on NHIS data
Objective To explore the main risk factors for the occurrence of depressive symptoms in children and adolescents,and to construct a nomogram model.Methods The eligible data collected by the 2022(American)National Health Interview Survey(NHIS)were selected for analysis,and the data mainly included the demographic characteristics of children and families.Least absolute shrinkage and selection operator(LASSO)analysis was used to preliminarily screen the predictors of depressive symptoms in children and adolescents,logistic regression was used for multivariate analysis,and finally,the nomogram of predictive symptoms of depressive symptoms was constructed with the screened independent risk factors.Results The average age of the group with depressive symptoms was(12.7±3.3)years,and the average age of the group without depressive symptoms was(11.7±3.5)years.Logistic regression analysis showed that female gender,older age,less physical activity,racial discrimination,living with people with mental illness or severe depression,having experienced or witnessing violence,having autism,having attention defi-cit and hyperactivity disorder(ADHD),and poor health were the main risk factors for depressive symptoms in chil-dren and adolescents(P<0.05).The C-index of the nomo-gram model of depressive symptoms in children and adoles-cents was 0.71,the predicted value of the calibration curve was basically consistent with the actual value,and the area under the ROC curve of the model was 0.712.Conclusion Gender,age,participation in physical activities,racial dis-crimination,living with people with mental illness or severe depression,having experienced orwitnessed violence,autism,ADHD,and health status are the main influencing factors for the occurrence of depressive symptoms in children and adolescents.

Children and adolescentsDepressive symptom(American)National Health Interview Survey(NHIS)Nomogram

王可、王晶晶、张虹

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徐州医科大学公共卫生学院卫生统计学教研室,江苏徐州 221004

默沙东研发(中国)有限公司,全球数据管理服务中心,北京 100012

徐州医科大学附属儿童医院急诊科,江苏徐州 221000

儿童青少年 抑郁症状 (美国)国家健康访谈调查(NHIS) 列线图

江苏省社会科学基金一般项目江苏省高等学校哲学社会科学研究一般项目徐州市重点研发计划社会发展项目

23SHB0062023SJYB1115KC23309

2024

中国校医
江苏省预防医学会 中华预防医学会

中国校医

影响因子:0.378
ISSN:1001-7062
年,卷(期):2024.38(2)
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