Objective To explore the characteristics of adverse drug reactions(ADR)in our hospital,and to provide references for rational drug use in clinical practice.Methods The ADR reports submitted to the National Adverse Drug Re-action Monitoring Center from January 2020 to September 2023 were retrospectively collected,and the gender,age,route of administration,type of ADR,types of drugs involved,organs/systems involved in ADR,and main clinical manifestations of the patients with ADR were analyzed.Results A total of 1 019 ADR reports were collected,including 761 cases(74.68％)of general type ADR,213 cases(20.90％)of severe ADR,and 45 cases(4.42％)of new ADR,with the highest number of ADRs caused by intravenous infusion administration(52.11％).The top three drugs that caused ADR were antitumor drugs(46.29％),anti-infective drugs(16.95％),and metabolic and endocrine system drugs(7.17％).Gastrointestinal system damage was the most common(21.87％),followed by hematologic system damage(16.14％),and skin and appendage damage(16.14％).Severe ADR was mainly manifested as bone marrow suppression(47.00％).Conclusion The clinical supervision of intravenous drug use,anti-tumor drugs,and anti-infective drugs should be strengthened,attention should be paid to ADR monitoring and reporting,and rational drug use should be promoted.
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