Analysis of the prevalence and risk factors of hyperuricemia among 1 686 older adults in Fuzhou City
Objective To investigate the prevalence of hyperuricemia(HUA)among urban and rural residents aged 60 and above in Fuzhou and analyze the influencing factors to provide a basis for the prevention and control of hyperuricemia in the elderly.Methods Multi-phase stratified cluster random sampling was used to recruit a total of 1 686 residents aged 60 years and above.Demographic information,dietary intake,and serological information on the participants were collected through questionnaires,physical examinations,and laboratory tests.The prevalence of HUA among patients with different chronic diseases was compared using the chi square test,a dietary model was developed using factor analysis,and the factors influencing hyperuricemia were analyzed by multivariate unconditional logistic regression.Results There were 579 HUA patients among 1 686 participants,with a prevalence of 34.3%,the prevalence in males was 32.9%and that in females was 35.6%.The prevalence of HUA among residents of different ages and the presence of overweight or obesity,abdominal obesi-ty,hypertension,hyperlipidemia,and diabetes varied,and the differences were statistically significant(P<0.05).Four dietary models were obtained through factor analysis:beverage and snack dietary patterns,balanced dietary patterns,grain and vege-table dietary patterns,and alcohol,livestock,poultry,and aquatic dietary patterns.The results of univariate unconditional lo-gistic regression analysis showed that a balanced dietary pattern was a protective factor for hyperuricemia(Q3:Q1 OR=0.743,95%CI:0.559-0.998,P=0.041),while an alcohol,livestock,poultry,and aquatic dietary pattern was a risk factor for hyperuricemia(Q4:Q1 OR=1.5 77,95%CI:1.184-2.101,P=0.002).The results of multiple factor unconditional logis-tic regression analysis showed that increased age,over-weight and obesity,abdominal obesity,hypertension,hyper-lipidemia,and the dietary pattern of alcohol,livestock,poultry,and aquatic products were risk factors for hyperuricemia(P<0.05),while the balanced dietary pattern was a protec-tive factor for hyperuricemia(P<0.05).Conclusions The prevalence of hyperuricemia among elderly residents in Fuzhou was relatively high.Older adults with chronic diseases such as hypertension,hyperlipidemia,and obesity are advised to take medication on time,measure blood pressure and blood lipids regularly,have a balanced diet,maintain a healthy weight,con-trol alcohol consumption,and reduce the intake of red meat and seafood.