Effectiveness of electronic bronchoscopic bronchoalveolar lavage as an ad-junct in the treatment of severe pneumonia complicated by pulmonary at-electasis in children
Objective This study was aimed at exploring the effects of bronchoalveolar lavage with electronic bron-choscope assistance in the treatment of severe pneumonia complicated with atelectasis among children.Methods A total of 92 children with severe pneumonia complicated with atelectasis admitted to our hospital between September 2019 and Sep-tember 2022 were selected and randomly divided into a control group and observation group.The control group comprised 46 children;three children lacked signed consent for study participation,and 43 children actually participated in the study.The children received conventional treatment.The observation group comprised 46 children;two children lacked signed consent for study participation,and 44 children actually participated in the study.The children received electronic bronchoscope bronchoalveolar lavage.After treatment,the disappearance time of cough,expectoration,and shortness of breath;total hospi-tal stay;and tumor necrosis factor(TNF-α),interleukin-6(IL-6),interleukin-8(IL-8),dynamic compliance(Cdyn),airway resistance(Raw),and other indicators were compared.Results The rate of treatment effectiveness in the observation group was 95.45％,and that in the control group was 79.07％;the difference was statistically significant(x2=5.286,P=0.021).After treatment,the disappearance time of cough,expectoration,and shortness of breath,and the total hospital stay were 8.56±1.33 days,6.25±0.75 days,and 18.16±3.15 days,respectively,in the observation group,and 12.34±1.89 days,9.04±1.45 days,and 24.15±3.46 days,respec-tively,in the control group.The difference was statistically significant.(t=10.808,11.310,8.447,all P＜0.001).After treatment,in the observation group,the TNF-α,IL-6,and IL-8 levels were 17.26±3.47 ng/L,3.46±0.87 ng/L,and 5.98±0.85 ng/L,respectively,whereas those in the control group were 23.55±3.91 ng/L,5.78±1.21 ng/L,and 9.12±1.13 ng/L,respectively;the difference was statistically significant.(t=7.941,10.286,14.669,all P＜0.001).After treat-ment,Cdyn was 35.74±6.14 mL/cmH2O in the observation group and 29.66±5.32 mL/cmH,O in the control group,with a statistically significant difference(t=4.931,P＜0.001).Raw was 9.64±1.91 cmH2O/(L·s)in the observation group and 12.45±2.47 cmH2O/(L·s)in the control group,with a statistically significant difference(t=5.944,P＜0.001).Conclusion Bronchoalveolar lavage with an electronic bronchoscope effectively improved the treatment efficiency,alleviat-ed inflammatory reactions,and improved lung function in children with severe pneumonia complicated with atelectasis,and therefore has high application value.
万方数据
维普
