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学龄前期及学龄期打鼾儿童的临床特点分析

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目的 分析学龄前期及学龄期打鼾儿童的临床及睡眠结构特点.方法 以2020年6月-2021年12月在甘肃省妇幼保健院因打鼾就诊的285名儿童为研究对象(打鼾组),选择同时期在该院健康体检的60名无打鼾儿童为对照组,根据年龄分为学龄前期组及学龄期组,收集打鼾就诊儿童的临床资料及多导睡眠监测结果.结果 学龄前期打鼾组儿童扁桃体和(或)腺样体肥大比例为88.9%,鼻炎/鼻窦炎比例为31.5%,相比于学龄期打鼾组的16.0%、78.0%,差异均有统计学意义(P均<0.05).学龄前期打鼾组儿童张口呼吸比例为75.3%,呼吸费力比例为35.7%,呼吸暂停比例为28.5%,夜尿比例为55.3%,相比于学龄前期对照组的43.3%、1 0.0%、1 0.0%及26.7%,差异均有统计学意义(P均<0.05).学龄期打鼾组儿童张口呼吸比例为80.0%,呼吸暂停比例为24.0%,注意力不集中比例为68.0%,相较于学龄期对照组的46.7%、6.7%及43.3%,差异均有统计学意义(P均<0.05).学龄前期打鼾组和学龄期打鼾组儿童非快动眼睡眠(NREM)1期比例、呼吸暂停低通气指数(AHI)、氧减指数(ODI)、睡眠效率(SE)、NREM3期比例及鼾声指数相较于学龄前期对照组和学龄期对照组,差异均有统计学意义(P均<0.05).学龄前期打鼾组儿童总睡眠时间(TST)、NREM1期比例相较于学龄期打鼾组,差异均有统计学意义(P均<0.05).学龄前期打鼾组儿童鼾声指数与AHI、ODI及NREM1期比例呈正相关,与NREM3期比例呈负相关(P均<0.05);学龄期打鼾组儿童鼾声指数与AHI、ODI及NREM1期比例呈正相关,与NREM3期比例、快动眼睡眠(REM)期比例呈负相关(P均<0.05).结论 学龄前期及学龄期打鼾儿童的病因及临床表现不同.不同年龄段打鼾儿童均存在睡眠结构紊乱,且学龄期打鼾儿童睡眠结构紊乱程度高于学龄前期.打鼾程度可作为评价儿童睡眠障碍的重要指标.
Analysis of the clinical characteristics in preschool and school-age chil-dren who snore
Objective To analyze the clinical and sleeping structure characteristics of preschool and school-age children who snore.Methods 285 children who snore admitted in our hospital from June 2020 to December 2021 were enrolled in this study.In addition,60 children who received a health examination in the children's health care department of our hospital were also included as controls during the same period.According to their age,these children were divided into the preschool-age group and the school-age group.Clinical data and polysomnography results were collected.Results The proportion of tonsil and/or adenoid hypertrophy was 88.9%,and the proportion of rhinitis/sinusitis was 31.5%in preschool-age children who snore,compared with 16.0%and 78.0%,respectively,in school-age children who snore.These differences were statistically significant(all P<0.05).The proportion of open-mouth breathing was 75.3%,the proportion of laborious breathing was 35.7%,the proportion of apnea was 28.5%,and the proportion of nocturia was 55.3%in preschool-age children who snore,compared with 43.3%,10.0%,10.0%and 26.7%,respectively,in preschool-age children in the control group.These differences were statistically significant(all P<0.05).The proportion of open-mouth breathing was 80.0%,the proportion of apnea was 24.0%,and the proportion of inattention was 68.0%in school-age children who snore,compared with 46.7%,6.7%and 43.3%,respectively,in school-age children in the con-trol group.These differences were statistically significant(all P<0.05).The proportion of non-rapid eye movement 1(NREM1)stage,apnea-hypopnea index(AHI),oxygen desat-uration index(ODI),sleeping efficiency(SE),proportion of non-rapid eye movement 3(NREM3)stage and snoring in dex in preschool and school-age children who snore were statistically significantly different compared to these parameters in preschool and school-age children in the control group(all P<0.05).The total sleep time and the proportion of NREM1 stage in preschool-age children who snore were statistically significantly different compared to these parameters in school-age chil-dren who snore(all P<0.05).The snoring index was positively correlated with AHI,ODI and the proportion of NREM1 stage,and negatively correlated with the proportion of NREM3 stage in preschool-age children who snore(all P<0.05).The snoring index was positively correlated with AHI,ODI and the proportion of NREM1 stage,and negatively correlated with the propor-tion of NREM3 stage and rapid eye movement(REM)stage in school-age children who snore(all P<0.05).Conclusions The clinical manifestations and causes of snoring in preschool and school-aged children are different.Children who snore in different age groups have disordered sleeping structure.The changes in sleeping structure in school-age children who snore are more obvious than those in preschool children.The degree of snoring can be used as an important index to evaluate chil-dren with sleep disorders.

SnoringChildrenPreschool-ageSchool-ageSleep structure

赵启君、王永军、王舒颖、李万怡、王文媛、张涛

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甘肃省妇幼保健院(甘肃省中心医院)小儿呼吸二科,甘肃兰州 730050

打鼾 儿童 学龄前期 学龄期 睡眠结构

兰州市科技计划项目

2022-5-77

2024

中国校医
江苏省预防医学会 中华预防医学会

中国校医

影响因子:0.378
ISSN:1001-7062
年,卷(期):2024.38(5)