Analysis of pathogenic bacteria detection characteristics and drug sensi-tivity test results in patients with severe liver disease and hospital infec-tion
Objective To explore the characteristics of pathogen detection and drug sensitivity test results in pa-tients with severe liver disease and hospital infection.Methods 93 patients with severe liver disease and hospital infection admitted to our hospital from January 2020 to January 2023 were selected as the research participants.Samples were collect-ed and sent for examination.Pathogen culture and drug sensitivity tests were conducted,and the characteristics of pathogen detection and main pathogen resistance were analyzed.Results A total of 125 pathogenic bacteria were detected in 93 patients,including 73 Gram negative bacteria(58.40％),46 Gram positive bacteria(36.80％),and 6 fungi(4.80％).Escherichia coli and Klebsiella pneumoniae accounted for a high proportion of the Gram negative bacteria;Staphylococcus aureus and Staphylococcus epidermidis accounted for a high proportion of the Gram positive bacteria.The main Gram negative bacteria showed no resistance to meropenem and imipenem,but high resistance to cefazolin,ceftazidime,and other antibiotics.The main Gram positive bacteria were not resistant to vancomycin and linezolid,but showed high resistance to penicillin,erythro-mycin,and other antibiotics.Conclusion Severe liver disease with hospital infection is mostly caused by Gram negative bacteria,drug sensitivity testing should be carried out as soon as possible and targeted medication should be used to promote the regression of the infection.
Severe liver diseaseHospital infectionPathogenic bacteriaDrug sensitivity results
万方数据
维普
