Objective To investigate the influencing factors for catheter-associated infection(CRBSI),to construct a prediction model,and to build up treatment strategies of the injection in patients with mainte-nance hemodialysis(MHD).Methods A total of 204 MHD patients in our hospital were selected as the con-trol subjects.They were divided into infected group(n=63)and non-infected group(n=141).Logistic regres-sion was used to analyze the patients'clinical data and to construct the model.A new intervention system was then established based on the model,clinical experience and literature reports.In addition,a total of 198 MHD patients were selected as the observation subjects to evaluate the effects of the new intervention system.Re-sults Diabetes history(OR=2.237,95％CI:1.067～5.679,P=0.003),catheter placement time(OR=3.647,95％CI:1.326～7.892,P=0.024),frequency of catheter care(OR=6.679,95％CI:2.534～16.476,P=0.003),aseptic training rate(OR=2.889,95％CI:1.146～6.654,P=0.030)and blood uric acid(OR=2.937,95％CI:1.627～8.883,P=0.014)were the independent influencing factors for CRBSI in MHD patients.The model equation was Y=-20.673+1.116×blood uric acid+1.012×aseptic training rate+2.017×catheter care frequency+1.912×catheterization time+1.079×diabetes history.Hosmer and Lemeshow's goodness of fit test equation was used(x2=10.678,P=0.236).Receiver operating characteristic curve showed that the area under the curve was 0.813,the sensitivity was 89.47％,and the specificity was 63.93％.The incidence of CRBSI and adverse events were lower in the observation group than those in the control group(x2=3.606 and 32.780;P＜0.001).Conclusion The prediction model has a better discrimination validity,and the evidence-based systematic nursing intervention system has a better effect on preventing and controlling CRBSI in MHD patients.
维普
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