活性维生素D对慢性肾脏病患者代谢及肾脏细胞功能的影响
Effects of the active form vitamin D on metabolism and kidney cell function in patients with chronic kid-nev disease
郭子仪 1张紫媛 2方敬爱2
作者信息
- 1. 030001 太原,山西医科大学第一临床医学院
- 2. 030001 太原,山西医科大学第一医院肾内科
- 折叠
摘要
维生素D(vitamin D,VD)是一种脂溶性类固醇衍生物,其不足或缺乏影响慢性肾脏病(chronic kidney disease,CKD)患者的钙磷稳态、甲状旁腺激素水平及血糖血脂代谢,从而导致一系列并发症的发生,降低CKD患者的生活质量及生存率.本文将围绕维生素D对慢性肾脏病患者代谢及肾脏细胞功能的作用机制进行综述,为CKD及其并发症的防治提供思路.
Abstract
Vitamin D is a lipid-soluble steroid derivative.Insufficiency or deficiency of vitamin D in pa-tients with chronic kidney disease(CKD)affects calcium-phosphorus homeostasis,parathyroid hormone(PTH)level and glucose and lipid metabolism,leading to the presence of a series of complications,lower qual-ity of life and reduced survival rate in CKD patients.This article reviews the mechanism of vitamin D on me-tabolism and kidney cell function in CKD patients to provide bases for the prevention and treatment of CKD and its complications.
关键词
维生素D/慢性肾脏病/钙磷稳态/甲状旁腺激素/糖脂代谢Key words
Vitamin D/Chronic kidney disease/Calcium-phosphorus homeostasis/Parathyroid hor-mone/Glucose and lipid metabolism引用本文复制引用
出版年
2024
NETL
NSTL
万方数据