Research progress in the relationship between hemodialysis-related complications and neutrophil/lym-phocyte ratio in hemodialysis patients
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近年来,中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)已被公认为一种新型预测生物标志物,由于其创伤小、经济、简便、敏感性和特异性高等优点,在心血管疾病、肾脏疾病、自身免疫性疾病等预后指标中广泛应用.血液透析(haemodialysis,HD)作为危重症或晚期肾病患者延长寿命的治疗手段,不可避免会导致很多并发症,因此及时识别和治疗HD相关并发症至关重要.有研究发现在HD相关并发症中NLR似乎具有一定的识别和预测能力,故本综述通过总结当前HD患者相关并发症中NLR研究进展,为临床医生评估HD患者相关并发症的发生和预后提供依据.
Currently,neutrophils to lymphocytes ratio(NLR)has been recognized as a new predictive biomarker,and is widely used as a prognostic indicator for cardiovascular diseases,renal diseases,autoim-mune diseases and others because it is less traumatic,economic,simple,high sensitive and specific.Hemodial-ysis(HD)is one of the essential measures for critically ill and end-stage renal disease patients to prolong their-lives,but many complications occur inevitably.Early identification and treatment of theses complications are required.Previous studies have found that NLR may have the abilities to recognize and predict HD-related complications.This review summarizes the research progress in NLR changes in HD-related complications,to provide a basis for clinicians to evaluate the presence and prognosis of HD-related complications.
HemodialysisNeutrophil to lymphocyte ratioComplicationsResearch progress