Objective To analyze the application of therapeutic plasma exchange(TPE)and its compli-cations in pediatric renal rheumatic diseases,and to explore the relevant nursing strategies.Methods The chil-dren undergoing TPE at the Department of Nephrology and Rheumatology,Fudan University Children's Hos-pital from January 2021 to December 2022 were retrospectively studied.Informed consent was obtained from the family of the patient.Vascular access was established through an internal jugular vein.The Prismaflex blood purification machine was used to perform TPE in a total of 28 times for 9 patients.The primary diseases of the patients,pre-and post-TPE indicators,and the presence of complications were analyzed.Results Com-plications occurred in the 28 times of TPE for the 9 patients,including allergic reactions 9 times(32.1％),hy-pocalcemia 9 times(32.1％),hypotension 4 times(14.2％),coagulation in extracorporeal circulation once(3.6％),and catheter malfunction once(3.6％).After appropriate nursing interventions,the complications were resolved,and TPE treatments completed successfully without any other life-threatening events.Conclusion In the processes of TPE,clinical efficacy on children with different diseases should be observed,and TPE complications should be monitored and managed by appropriate nursing interventions to minimize the side-ef-fects of complications,and to ensure the safety and efficacy of TPE.
NETL
NSTL
万方数据
