慢性肾脏病及血液透析血栓形成的相关机制研究进展
Research progresses in the mechanism of thrombosis in chronic kidney disease and hemodialysis pa-tients
徐娅 1夏运风1
作者信息
- 1. 400016 重庆,重庆医科大学附属第一医院肾脏内科
- 折叠
摘要
肾脏损伤带来人体内环境紊乱,可损伤内皮细胞、激活血小板及凝血纤溶系统,使机体处于高凝状态,促进血栓形成.动静脉异常血栓形成是各种肾脏疾病的常见、多发的并发症,严重影响患者预后,尤其是在肾病综合征、慢性肾脏病以及维持性血液透析患者群体中.了解各种肾脏疾病中血栓形成机制对制定抗凝方案、改善患者预后有着重大意义.
Abstract
Kidney injury causes the derangement of homeostasis,which damages endothelial cells,and activates platelets,blood coagulation and fibrinolysis system,leading to a hypercoagulation state to facilitate thrombosis.Thrombosis in arteries and veins is a common and frequent complication of various kidney diseas-es,seriously affecting the prognosis of patients,especially in patients with nephrotic syndrome,chronic kid-ney disease and maintenance hemodialysis patients.Understanding the mechanism of thrombosis in various kidney diseases is of great importance for developing anticoagulation regimens and improving patient progno-sis.
关键词
肾病综合征/慢性肾脏病/透析/凝血/血栓形成Key words
Nephrotic syndrome/Chronic kidney disease/Dialysis/Coagulation/Thrombosis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据