Kidney injury causes the derangement of homeostasis,which damages endothelial cells,and activates platelets,blood coagulation and fibrinolysis system,leading to a hypercoagulation state to facilitate thrombosis.Thrombosis in arteries and veins is a common and frequent complication of various kidney diseas-es,seriously affecting the prognosis of patients,especially in patients with nephrotic syndrome,chronic kid-ney disease and maintenance hemodialysis patients.Understanding the mechanism of thrombosis in various kidney diseases is of great importance for developing anticoagulation regimens and improving patient progno-sis.
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