《Sepsis-associated acute kidney injury(SA-AKI):28th Acute Disease Quality Initiative work-group:The ADQI Consensus Report》(hereinafter referred to as Consensus)was published in February 2023.The consensus covers six parts of clinical definition and epidemiology,pathophysiology,the impact of fluid management strategies,the role of biomarkers in risk stratification and diagnostic treatment guidance,extra-corporeal blood purification and innovative therapies,and SA-AKI in pediatric patients,totaling 34 articles of consensus.This consensus is the first global ADQI expert consensus on SA-AKI,and provides a more accurate direction and framework for the diagnosis and treatment of SA-AKI.This article interprets the main points of adults in the first 5 parts of the consensus,and shares the application experience of West China Hospital of Si-chuan University in SA-AKI blood purification,which can provide reference for medical workers in the diag-nosis and treatment of SA-AKI.