Objective To investigate the maturation rate of autologous arteriovenous fistula(AVF)in peritoneal dialysis(PD)patients,and to explore the influencing factors for AVF failure in PD patients.Meth-ods Patients on PD undergoing AVF surgery for the first time in the hospital between January 1,2018 and June 30,2023 were enrolled in this study.According to whether the AVF maturation with assistance,the pa-tients were divided into the non-assisted AVF maturation group and the non-assisted AVF failure group.Base-line data were compared between the two groups.Multivariate logistic regression was used to analyze the in-fluencing factors for AVF failure.Results A total of 116 PD patients were enrolled in this study.The non-as-sisted AVF maturation rate was 76%and the assisted AVF maturation rate was 93%.In the non-assisted AVF failure group,female proportion was higher(χ²=10.830,P=0.001),mean arterial pressure was lower(t=3.106,P=0.002),ratio of diabetes as the primary disease was higher(χ²=4.087,P=0.043),and preoperative hemoglo-bin level was higher(t=-2.376,P=0.019).Multivariate logistic regression showed that female(OR=4.813,95%CI:1.736~13.339,P=0.003)and mean arterial pressure(OR=0.960,95%CI:0.927~0.995,P=0.024)were the independent risk factors for AVF failure in PD patients.Conclusions The maturation rate of the first AVF in PD patients is similar to that in general population.Females and lower preoperative mean arterial pres-sure are associated with poor AVF maturation in PD patients.