首页|抗磷脂抗体在血液透析患者自体动静脉内瘘相关并发症中的研究进展

抗磷脂抗体在血液透析患者自体动静脉内瘘相关并发症中的研究进展

Research progress of antiphospholipid antibody in the autologous arteriovenous fistula-related compli-cations in hemodialysis patients

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血液透析(hemodialysis,HD)是危重患者最常用的血液净化技术之一,但不可避免由于各种因素存在会导致许多并发症.其中自体动静脉内瘘(arteriovenous fistula,AVF)相关并发症是HD患者治疗失败和死亡的重要原因之一.有研究发现HD患者中普遍存在抗磷脂抗体(antiphospholipid antibody,aPL)持续阳性,似乎aPL阳性与AVF相关并发症之间存在一定关联.因此为了改善HD患者预后,减少AVF相关并发症发生,本文拟通过总结当前aPL在HD患者AVF相关并发症中的研究进展,为临床HD患者预防和治疗AVF相关并发症提供依据.
Hemodialysis(HD)is one of the most commonly used blood purification techniques for criti-cally ill patients,but it will inevitably lead to many complications due to various factors.Among them,compli-cations related to arteriovenous fistula(AVF)are one of the important causes for treatment failure and death in HD patients.Some studies have found that persistently positive antiphospholipid antibody(aPL)is commonly present in HD patients,which may be involved in the AVF-related complications.This paper summarizes the current research progress of aPL in AVF-related complications in HD patients,in order to improve the progno-sis of HD patients with AVF-related complications and to provide bases for the prevention,monitoring and treatment of the complications.

Antiphospholipid antibodyHemodialysisArteriovenous fistulaComplication

李甜、伍杨、王学良、苑书婷、何喜梅、万立平、席春生

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730050 兰州,中国人民解放军联勤保障部队第九四○医院肾脏病科

730000 兰州,甘肃中医药大学第一临床医学院

抗磷脂抗体 血液透析 动静脉内瘘 并发症

2024

中国血液净化
中国医院协会

中国血液净化

CSTPCD
影响因子:1.54
ISSN:1671-4091
年,卷(期):2024.23(12)