Study on nanofiltration technology and drying method of Astragalus membranaceus ultrafiltrate
Objective:To establish the nanofiltration concentration process and drying method of Astragalus membranaceus ultrafiltrate.Methods:Using Astragalus methyloside,Pistil isoflavone glucoside,Pistil isoflavone,mangiferin,Astragalus polysaccharide,ethanol extract as evaluation indexes,and filtration temperature,operating pressure,cross flow rate as investigation factors,the optimal nanofiltration process of Astragalus ultrafiltrate was selected by AHP entropy weight method and L9(34)orthogonal design method;the effects of freeze drying,vacuum drying,atmospheric pressure drying and microwave drying on nanofiltrate were compared and the best drying method for nanofiltration concentrates was selected by a combination of comprehensive scoring and fingerprinting.Results:The optimal nanofiltration process of Astragalus ultrafiltrate was pressure 0.16 MPa,temperature 40℃and cross flow rate 4.5 m·s-1.The best drying method for filtrate was vacuum drying.Conclusion:This study can provide a technology with energy saving and environmental protection for the industrial production of high quality Astragalus extract.