Current status of B-cell targeted therapy in systemic lupus erythematosus
Systemic lupus erythematosus(SLE)is a highly heterogeneous autoimmune disease with complex pathogenesis and diverse clinical manifestations,which makes it difficult to achieve standard treatment and long-term improvement of prognosis.In recent years,with continuous exploration of the pathogenesis of SLE,new drugs targeting different targets have emerged,such as T cells,B cells,typeⅠ interferon and intracellular signaling molecules,among which B cells and their related molecules have been attracting much attention as an important target for SLE treatment.In this article,we focus on the latest research results and application of B-cell-targeted therapy in SLE,with a view to provide reference for clinical treatment.
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