首页|金天格胶囊治疗绝经后骨质疏松症的药物经济学评价

金天格胶囊治疗绝经后骨质疏松症的药物经济学评价

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目的:比较金天格胶囊和仙灵骨葆胶囊治疗绝经后骨质疏松症的经济性.方法:采用多中心前瞻性观察性队列研究设计,收集自然绝经1 年以上女性骨质疏松患者的相关信息,分为金天格胶囊联合双膦酸盐类治疗组(金天格组)和仙灵骨葆胶囊联合双膦酸盐类治疗组(仙灵骨葆组),并进行随访.基于中国卫生系统角度,采用倾向值匹配方法控制混杂,并对2 种治疗方案进行药物经济学评价.结果:金天格组比仙灵骨葆组患者高0.016 QALYs,直接医疗成本高822 元,增量成本效用比为 51 375 元·QALY-1,低于2022年1 倍中国人均GDP.结论:相较于仙灵骨葆组,金天格组用于治疗绝经后骨质疏松症更具有经济性.
Economic evaluation of Jintiange capsule in the treatment of postmenopausal osteoporosis
Objective:To evaluate the cost-effectiveness of Jintiange Capsule and Xianlinggubao Capsule for the treatment of postmenopausal women with osteoporosis.Methods:A multicenter,prospective,observational cohort study was carried out to collect information about female patients with osteoporosis who had been naturally menopausal for more than one year.The patients were divided into two groups:the Jintiange capsule combined with bisphosphonates group(Jintiange group)and the Xianlinggubao capsule combined with bisphosphonates group(Xianlinggubao group).The patients were followed up for observation.Based on the healthcare system perspective in China,a propensity score matching method was used to control for confounders and pharmacoeconomic evaluation of the two treatment regimens was performed.Results:The Jintiange group yielded an additional 0.016 QALYs and an additional cost of 822 yuan,so the ICER was 51 375 yuan·QALY-1,which was lower than China's per capita GDP in 2022.Conclusion:Jintiange capsule combined with bisphosphonates group is likely to be a cost-effective treatment compared with Xianlinggubao capsule plus bisphosphonates group for the treatment of postmenopausal osteoporosis.

postmenopausal osteoporosiscost-utilitycohort studyJintiange capsuleXianlinggubao capsule

彭楠、李珊珊、余江霞、官海静

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中国药科大学国际医药商学院,南京 211198

北京大学中国卫生经济研究中心,北京 100080

贵州医科大学医药卫生管理学院,贵阳 550025

首都医科大学附属北京天坛医院,北京 100070

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绝经后骨质疏松症 成本效用 队列研究 金天格胶囊 仙灵骨葆胶囊

2024

中国新药杂志
中国医药科技出版社 中国医药集团总公司 中国药学会

中国新药杂志

CSTPCD北大核心
影响因子:1.039
ISSN:1003-3734
年,卷(期):2024.33(13)
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