Cinacalcet hydrochloride is the first commercially available calciumimetic agent.Amgen obtained it through authorization from NPS Pharmaceutical.This study searches and analyzes the patents of cinacalcet,focusing on its core patents,layout patents,and related patent disputes,in order to provide information references for Chinese pharmaceutical enterprises in drug patent mining and layout.This study obtains the following insights:by utilizing the patent extension system and selecting the timing of patent applications,the market monopoly period of drugs can be effectively extended;after introducing projects from outside,pharmaceutical companies should actively carry out innovation exploration and patent layout to establish a strict patent wall.