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肺炎球菌结合疫苗临床研究进展

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肺炎球菌性疾病对人群健康、社会经济造成了较大的影响,已成为全球值得关注的公共卫生问题之一.目前肺炎球菌性疾病已被WHO列为需"极高度优先"使用疫苗预防的疾病.肺炎球菌疫苗主要包括肺炎球菌多糖疫苗和肺炎球菌结合疫苗.本文将以美国FDA批准的几款肺炎球菌结合疫苗为重点,简要介绍肺炎球菌结合疫苗的临床研究进展,以期为肺炎球菌结合疫苗的临床研发思路提供参考.
Progress of clinical research on pneumococcal conjugate vaccine
Pneumococcal disease has caused a significant impact on human health and social economy.It has become one of the public health problems worthy of attention in the world.The WHO classified pneumococcal disease as a"very high priority"for vaccine prevention.Pneumococcal vaccines mainly include pneumococcal polysaccharide vaccine and pneumococcal conjugate vaccine.This article focuses on several FDA-approved pneu-mococcal conjugate vaccines to briefly introduce the clinical research progress of pneumococcal conjugate vaccines,in order to provide reference for the clinical research and development of pneumococcal conjugate vaccine.

streptococcus pneumoniaeinvasive pneumococcal diseasepneumoniapneumococcal conjugate vaccineresearch strategy

刘琳玉、李英丽

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国家药品监督管理局药品审评中心,北京 100076

肺炎链球菌 侵袭性肺炎球菌性疾病 肺炎 肺炎球菌结合疫苗 研发策略

2024

中国新药杂志
中国医药科技出版社 中国医药集团总公司 中国药学会

中国新药杂志

CSTPCD北大核心
影响因子:1.039
ISSN:1003-3734
年,卷(期):2024.33(15)
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