Introduction and comparison of alternative and optimization methods for quality-adjusted life-year in health value assessment
Quality-adjusted life-year(QALY)is an important health outcome indicator in pharmacoeconomic evaluation and value assessment.However,the QALY theory and the assumptions in application have been challenged in recent years,such as discrimination against the elderly,the disabled,or the patients with chronic diseases,inability to accurately reflect patient preference,and the failure to consider non-health benefits.Therefore,the development of better health outcome indicators has become an urgent issue.This study introduces the alternative and optimization methods for QALY,and comprehensively compares the advantages and disadvantages of different methods with QALY.We aim to promote further research and application of these methods,to provide a methodological reference for identifying better health outcome indicators in the future,and to facilitate the application and development of health technology assessment in China.
value assessmentquality-adjusted life-yearhealth outcome indicatorpharmacoeconomic evaluationhealth technology assessmentalternative and optimization methods