左房心外膜脂肪体积及密度对心房颤动冷冻球囊消融术后复发的影响
The impact of left atrial epicardial adipose tissue volume and density on the recurrence of atrial fibrillation after cryo-balloon ablation
任心畅 1林伟 2陈芳 1木炳武 1易琥珀1
作者信息
- 1. 上海大学附属第三医院(温州市人民医院)放射科(浙江温州 325000)
- 2. 上海大学附属第三医院(温州市人民医院)心内科(浙江温州 325000)
- 折叠
摘要
目的 探讨左房(LA)心外膜脂肪组织(EAT)体积及密度对心房颤动(简称房颤)冷冻球囊消融(CBA)术后复发的影响.方法 随访59例房颤CBA术前接受心脏CT血管造影(CCTA)的患者,房颤复发为随访终点,最终纳入52例患者(复发16例,无复发36例).通过CCTA定量测量LA体积、EAT体积、LA-EAT体积及LA-EAT密度,比较两组患者的差异.结果 16例(30.77％)患者CBA术后出现房颤复发.与无复发组相比,复发组体重指数(BMI)更大[(25.74±2.97)kg/m2 vs(23.99±2.38)kg/m2,P=0.044],LA 体积更大[(163.00+47.70)cm3 vs(122.70±30.96)cm3,P=0.001],LA-EAT 体积更大[(22.18±6.67)cm3 vs(17.70±3.37)cm3,P=0.025],LA-EAT 密度更高[(-74.73±5.67)HU vs(-79.80±5.78)HU,P=0.005].Pearson 相关分析显示,BMI 与 EAT体积、BMI 与 LA-EAT 体积之间存在弱但显著的相关性(r=0.343,P=0.013;r=0.338,P=0.014).Kaplan-Meier分析显示,LA-EAT体积较大(＞17.73 cm3)及LA-EAT密度较高(＞-80.81 HU)的患者有着更高的术后房颤复发率(Log-rank,P=0.020;P=0.022).结论 CBA术后复发组与无复发组相比,LA体积及LA-EAT体积更大,LA-EAT密度更高.
Abstract
Objective To investigate the impact of the left atrial(LA)epicardial adipose tissue(EAT)volume and density on the recurrence of atrial fibrillation(AF)after cryoballoon ablation(CBA).Methods A total of 59 pa-tients who underwent cardiac computed tomography angiography(CCTA)before cryoballoon ablation(CBA)of AF were following-up.AF recurrence was the endpoint of the follow-up,and ultimately,52 patients were included in the analysis(16 with recurrence and 36 without recurrence).The LA volume,EAT volume,LA-EAT volume,and LA-EAT density were quantified by CCTA,and were compared between the two groups of patients.Results 16 pa-tients(30.77％)had recurrence of AF after CBA.Compared with the non-recurrence group,the recurrence group had higher body mass index(BMI)[(25.74±2.97)kg/m2 vs(23.99±2.38)kg/m2,P=0.044],larger LA volume[(163.00 ±47.70)cm3 vs(122.70±30.96)cm3,P=0.001],larger LA-EAT volume[(22.18±6.67)cm3 vs(17.70±3.37)cm3,P=0.025],and higher LA-EAT density[(-74.73±5.67)HU vs(-79.80±5.78)HU,P=0.005].Pearson correlation a-nalysis showed weak but significant correlations between BMI and EAT volume(r=0.343,P=0.013),as well as between BMI and LA-EAT volume(r=0.338,P=0.014).Kaplan-Meier analysis showed that patients with larger LA-EAT volume(＞17.73 cm3)and higher LA-EAT density(＞-80.81 HU)had a higher postoperative AF recurrence rate(Log-rank,P=0.020;P=0.0 2 2).Conclusion Compared to the non-recurrence group,the recurrence group has significantly larger LA volume and LA-EAT volume,as well as higher LA-EAT density.[Chinese Journal of Cardiac Pacing and Electrophysiology,2024,38(1):22-26]
关键词
心血管病学/心房颤动/心外膜脂肪组织/冷冻球囊消融术/体层摄影术,螺旋计算机Key words
Cardiology/Atrial fibrillation/Epicardi-al adipose tissue/Cryoballoon ablation/Tomography,spiral computed引用本文复制引用
基金项目
温州市科学技术局基础科研项目(Y20220462)
出版年
2024
NETL
NSTL
万方数据