Anatomical position of inferior pulmonary veins on the impact of time to isolation≤60 s in cryoballoon ablation
Objective To analysis the anatomical position of inferior pulmonary veins on the impact of TTI(time to isolation)≤60 s in cryoballoon ablation(CBA).Methods Investigated patients with symptomatic atrial fibrilla-tion(AF)who had undergone CBA from January 2022 to June 2022 in our hospital.Computed Tomography(CT)an-giography of pulmonary vein were scaned in preoperation.We measured the ventral angle between the vertical line and the direction of each PV trunk(PV angle)on the transverse plane of enhanced CT images.The duration of cryo-balloon applications,balloon nadir temperature,interval thaw time at 0℃ and TTI of inferior pulmonary veins were recorded.According to the TTI,patients were divided into two groups(TTI≤60 s group,TTI>60 s group).Receiver operating characteristic(ROC)curve were used to assess predictive function of PV angle for predicting the success rate of TTI≤60 s.Results Twenty-five patients were enrolled In TTI≤60 s group,the duration of cyroballoon applications were notably shorter and balloon nadir temperature were more cooler than that in TTI>60 s group(all P<0.05).The PV angle of RIPV and LIPV in TTI≤60 s group were significantly more than that in TTI>60 s group[(116.2±8.4)°vs(102.4±4.4)°;(116.7±8.5)°vs(107.1±9.5)°,all P<0.05].With ROC analysis,The area un-der curve(AUC)of PV angle of RIPV on prediction for TTI≤60 s was 0.95(P=0.000).The AUC of PV angle of LIPV on prediction for TTI≤60 s was 0.776(P=0.019).Conclusion The difficulty of CBA is better predicted through CT angiography of pulmonary veins in preoperation.[Chinese Journal of Cardiac Pacing and Electrophys-iology,2024,38(3):161-164]