首页|深部室间隔起搏与左束支起搏在完全性房室传导阻滞患者中的对比研究

深部室间隔起搏与左束支起搏在完全性房室传导阻滞患者中的对比研究

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目的 通过深部室间隔起搏(deep ventricular septal pacing,DVSP)与左束支起搏(left bundle branch pa-cing,LBBP)的对比分析,探讨两种起搏策略在临床应用中的差异及其优缺点。方法 选取完全性房室传导阻滞(complete atrioventricular block,CAVB)患者共100例,随机分为DVSP组和LBBP组,每组50例。比较两组术中电极植入深度、QRS波时限、透视时间,术中、术后的电学参数(起搏阈值、心室感知、电极阻抗)、术中并发症发生情况,以及术前术后心脏功能(LVEF和NT-proBNP)的变化。结果 术中DVSP组电极植入深度(7。29±0。35)mm较LBBP组(8。00±0。41)mm略浅(P<0。05),DVSP组QRS波时限(119。56±4。65)ms较LBBP(111。72±7。00)ms组略宽(P<0。05),DVSP组透视时间(6。30±1。12)较LBBP组(11。40±2。07)更短(P<0。05);术中DVSP组比LBBP组起搏阈值更低(P<0。05),心室感知更好(P<0。05);DVSP组术中并发症发生率比LBBP组更低(P<0。05)。术后随访1年,两组电学参数无明显差异(P>0。05);两组患者心脏功能(LVEF和NT-proBNP)未出现负面影响(P>0。05)。结论 DVSP与LBBP技术对比,能达到良好的心室同步化效果,且操作相对更简单,可作为心室起搏依赖患者的策略之一。
Comparison of deep ventricular septal pacing and left bundle branch pacing in patients with complete atrial ventricular block
Objective To compare the advantages and disadvantages of two pacing strategies in clinical application by analyzing the deep ventricular septal pacing (DVSP)and left bundle branch pacing (LBBP). Methods A total of 100 patients suffer from complete atrioventricular block (CAVB)were randomly divided into DVSP group and LBBP group,with 50 cases in each group.The implantation depth,QRS duration,fluoroscopy time,intraoperative and postoperative electrical parameters (pacing threshold,ventricular perception,electrode impedance),intraoperative complications,and postoperative cardiac function (left ventricular ejection fraction and NT-proBNP)were compared between the two groups. Results The electrode implantation depth of DVSP group (7.29±0.35)mm was slightly shallower than that of LBBP group (8.00±0.41)mm (P<0.05),QRS duration of DVSP group (119.56±4.65)ms was slightly longer than that of LBBP group (111.72±7.00)ms (P<0.05),and fluoroscopy time of DVSP group (6.30±1.12)was less than that of LBBP group (11.40±2.07)(P<0.05);the pacing threshold of DVSP group was lower than that of LBBP group (P<0.05),and the ventricular perception was better (P<0.05);the incidence of in-traoperative complications in DVSP group was lower than that in LBBP group (P<0.05).After 1 year of follow-up,there was no significant difference in electrical parameters between the two groups (P>0.05),and the cardiac func-tion of the two groups was not significantly negatively affected as well(P>0.05). Conclusion Compared with LBBP,DVSP operation is relatively simpler,which can be used as one of the pacing strategies for patients with ven-tricular pacing dependence.

CardiologyDeep ventricular septal pacingLeft bundle branch pacingComplete atrioventricular blockElectrode implantation depthQRS durationFluoroscopy timeElectrical parametersCardiac function

杨鹏、林琦、谢敏、陈敏

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成都市第七人民医院天府院区心内科,四川成都 610000

心血管病学 深部室间隔起搏 左束支起搏 完全性房室传导阻滞 电极植入深度 QRS波时限 透视时间 电学参数 心脏功能

2024

中国心脏起搏与心电生理杂志
中国生物医学工程学会 武汉大学人民医院

中国心脏起搏与心电生理杂志

CSTPCD
影响因子:0.563
ISSN:1007-2659
年,卷(期):2024.38(6)