心脏电生理平衡指数对急性ST段抬高型心肌梗死患者左室重构的预测价值
Predictive value of cardiac electrophysiological balance index for left ventricular remodeling in patients with acute ST-segment elevation myocardial infarction
邓祖艳 1朱巧敏 1郭静 1朱夏玲1
作者信息
- 1. 丽水市中心医院,浙江丽水 323000
- 折叠
摘要
目的 分析心脏电生理平衡指数(iCEB)对急性ST段抬高型心肌梗死(STEMI)患者左室重构(LVR)的预测价值.方法 选择丽水市中心医院心内科2021年1月至2022年10月收治STEMI患者124例为研究对象,根据治疗后6个月是否发生LVR分为LVR组(n=36)和非LVR组(n=88).通过电子病历收集患者的临床资料,并进行比较.采用多因素Logistics回归分析LVR影响因素,并以ROC评价iCEB对LVR的预测价值.结果 两组梗死面积、总胆固醇、NT-proBNP和iCEB比较具有统计学差异(P<0.05);多因素Logistics回归分析结果显示,梗死面积、总胆固醇、NT-proBNP和iCEB是STEMI患者PCI术后发生LVR的独立影响因素(P<0.05);ROC分析结果显示,iCEB预测STEMI患者PCI术后LVR曲线下面积为0.912,最佳截断值为4.25,灵敏度为85.86％,特异度为83.97％;iCEB≥4.25的STEMI患者PCI术后不良心脏事件总发生高于iCEB<4.25患者,差异具有统计学意义(P<0.05).结论 iCEB可较为准确预测STEMI患者PCI术后LVR发生.
Abstract
Objective The predictive value of cardiac electrophysiological balance index (iCEB )for left ventricu-lar remodeling (LVR )in patients with acute ST-segment elevation myocardial infarction (STEMI ). Methods A total of 124 patients with STEMI admitted to the Department of Cardiology of Lishui Central Hospital from Janu-ary 2021 to October 2022 were selected as the study subjects.According to whether LVR occurred at 6 months af-ter treatment,they were divided into LVR group (n=36 )and non-LVR group (n=88 ).The clinical data of pa-tients were collected through electronic medical records and compared.Multivariate Logistics regression was used to analyze the influencing factors of LVR,and ROC was used to evaluate the predictive value of iCEB for LVR. Re-sults There were significant differences in infarct size,total cholesterol,NT-proBNP and iCEB between the two groups (P<0.05 ).Multivariate Logistics regression analysis showed that infarct size,total cholesterol,NT-proBNP and iCEB were independent influencing factors of LVR in STEMI patients after PCI (P<0.05 ).ROC a-nalysis showed that the area under the curve of iCEB predicting LVR after PCI in STEMI patients was 0.912,the best cut-off value was 4.25,the sensitivity was 85.86％,and the specificity was 83.97％.The total incidence of adverse cardiac events after PCI in STEMI patients with iCEB≥4.25 was higher than that in patients with iCEB<4.25,and the difference was statistically significant (P<0.05). Conclusions iCEB can accurately predict the oc-currence of LVR in STEMI patients after PCI.
关键词
心血管病学/心脏电生理平衡指数/急性ST段抬高型心肌梗死/左室重构/受试者工作特征曲线/不良心脏事件Key words
Cardiology/Cardiac electrophysiological balance index/Acute ST-segment elevation myocardial infarction/Left ventricular remodeling/Receiver operating characteristic curve/Adverse cardiac events引用本文复制引用
出版年
2024
NETL
NSTL
万方数据