摘要
目的 探讨餐后血脂水平检测对我国成人动脉粥样硬化性心血管疾病(ASCVD)风险预测的意义.方法 整群抽取2020年8月～9月于中国人民解放军总医院第六医学中心进行健康体检的35～74岁人群共979例,完善问卷调查、体格检查;分别测定其空腹及统一标准早餐后2 h的餐后血脂水平.对空腹与餐后血脂代谢特点及其与各体格测量指标:体质指数(BMI)、腰高比(WHtR)、腰围(WC)间的相关性进行分析.结果 35～74岁人群自身空腹与餐后血脂水平相比,餐后三酰甘油(TG)水平较空腹时明显增高,餐后总胆固醇(TC)和高密度脂蛋白胆固醇(HDL-C)水平较空腹时均有所降低,差异均具有统计学意义(P＜0.001);而空腹和餐后低密度脂蛋白胆固醇(LDL-C)水平比较无统计学差异(P＞0.05).成人空腹及餐后TG与BMI、WHtR、WC均呈正相关(P＜0.01);空腹及餐后HDL-C与BMI、WHtR、WC均呈负相关(P＜0.01).餐后TG与BMI、WHtR、WC相关性均大于空腹TG.结论 35～74岁人群餐后血脂与BMI、WHtR、WC相关性强,与空腹血脂一样可进行ASCVD风险的评估和预测.
Abstract
Objective To discuss the significance of detection of postprandial blood lipid level for predicting risk of atherosclerotic cardiovascular disease(ASCVD)in Chinese adults.Methods The cases aged from 35 to 74(n=979)were chosen by cluster sampling from the Sixth Medical Center,Chinese PLA General Hospital from Aug.2020 to Sept.2020.A questionnaire survey and physical examination were completed.The levels of fasting blood fat and postprandial blood lipid level 2 h after uniform breakfast were detected respectively.The metabolism features of fasting postprandial blood lipid levels,and correlation among them and body mass index(BMI),waist-to-height ratio(WHtR)and waist circumference(WC)were analyzed.Results In population aged from35 to 74,the comparison in fasting and postprandial blood lipid levels showed that level of postprandial triglyceride(TG)increased significantly that fasting TG,postprandial total cholesterol(TC)and high-density lipoprotein-cholesterol(HDL-C)levels decreased than fasting TC and HDL-C(P<0.001),and fasting and postprandial low-density lipoprotein-cholesterol(LDL-C)levels had no statistical difference(P>0.05)in adults.The levels of fasting and postprandial TG were positively correlated to BMI,WHtR and WC(P<0.01).The levels of fasting and postprandial HDL-C were negatively correlated to BMI,WHtR and WC(P<0.01).The correlation among postprandial TG level,BMI,WHtR and WC was higher than that among fasting TG level,BMI,WHtR and WC.Conclusion The postprandial blood lipid level is closely correlated to BMI,WHtR and WC,which,as fasting blood lipid level,can be taken in reviewing and predicting ASCVD risk as fasting blood lipid level in population aged from35 to 74.
基金项目
解放军总医院第六医学中心创新培育基金(CXPY201925)
NETL
NSTL
维普
万方数据