目的 系统评价基于微信的血压管理模式对高血压患者血压水平、服药依从性的影响.方法 通过PubMed、EMbase、Web of Science、Cochrane Library、中国知网(CNKI)、中国生物医学服务系统(Sinomed)、万方数据知识服务平台(WanFang Data)、维普(VIP)8个数据库,检索从建库至2022年9月有关微信干预对高血压患者血压管理的中英文文献.由两名研究人员根据Cochrane偏倚风险评估工具进行分析和评估后,采用RevMan5.4软件进行Meta分析.结果 本研究纳入46项随机对照试验,共7919例患者,其中实验组3961例,对照组3958例.Meta分析结果表明:与常规干预相比,微信干预能有效降低高血压患者的收缩压(MD=-12.19,95％CI:-14.65～-9.73,P＜0.00001)、舒张压(MD=-8.82,95％CI:-10.44～-7.20,P＜0.00001),提高血压达标率(OR=3.7,95％CI:2.35～5.82,P＜0.0001),明显改善高血压患者的服药依从性(OR=5.06,95％CI:3.29～7.77,P＜0.00001).结论 微信干预对高血压患者的血压管理有显著的积极影响,未来还需更多的设计规范、干预期长的高质量研究,为基于微信干预的血压管理提供强有力证据,解决患者日益增长的保健需求.
Abstract
Objective To review systematically the influence of health management based on WeChat on level of blood pressure(BP)and medication compliance in hypertensive patients.Methods The databases of PubMed,EMbase,Web of Science,Cochrane Library,CNKI,Sinomed,WanFang Data and VIP were retrieve for searching Chinese and English literature about BP management based on WeChat in hypertensive patientsfrom database establishment time to Sept.2022.The literature was given a Meta-analysis by using RevMan5.4 softwareafter analyzing and assessing according to Cochrane assessment tool for risk of bias by 2 researchers.Results The study included 46 randomized controlled trials(RCT)with a total of 7919 patients,including 3961 patients in test group and 3958 patients in control group.The results of Meta-analysis showed that WeChat intervention,compared with routine intervention,can effectively reduce systolic blood pressure(MD=-12.19,95％CI:-14.65～-9.73,P＜0.00001)and diastolic blood pressure(MD=-8.82,95％CI:-10.44～-7.20,P＜0.00001),increase BP compliance rate(OR=3.7,95％CI:2.35～5.82,P＜0.0001),and improve significantly medication compliance(OR=5.06,95％CI:3.29～7.77),P＜0.00001)in hypertensive patients.Conclusion WeChat intervention has a significant positive impact on BP management in hypertensive patients,and more high-quality studies with standardized design and long intervention period are needed in the future to provide strong evidence on BP management based on WeChat intervention and address the growing healthcare needs of hypertensive patients.
维普
万方数据