Objective To investigate the predictive value of dual nuclide myocardial imaging to long-term major adverse cardiovascular events(MACE)in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods AMI patients(n=95)were retrospectively chosen from the First Affiliated Hospital of Xinjiang Medical University from Jan.2015 to Dec.2020,and they were followed up for 3 y.All patients were divided,according to MACE occurrence after PCI,into MACE group(n=42)and control group(n=53).The differences in clinical characteristics and parameters related to dual nuclide myocardial imaging were compared between 2 groups.The predictive value of parameters related to dual nuclide myocardial imaging to MACE was analyzed.Results The incidence of diabetes increased significantly(42.86%vs.22.64%,P=0.035),severity of coronary stenosis increased significantly[(73.67±11.57)%vs.(66.11±8.69)%,P<0.001],left ventricular ejection fraction(LVEF)decreased significantly(47.45±3.83 vs.52.13±4.31,P<0.001),the total score of myocardial ischemia increased significantly[(14.29±4.20)%vs.(9.89±3.33)%,P<0.001],and mismatch percentage of myocardial perfusion/metabolism increased significantly(16.58±1.61 vs.15.69±2.14,P=0.028)in MACE group compared with control group.LVEF had some predictive value to MACE after PCI(AUC=0.777,95%CI:0.686~0.868,P<0.001).The severity of coronary stenosis and the total score of myocardial ischemia had some predictive value to MACE after PCI(AUC=0.676,AUC=0.784).The results of multi-factor Logistics regression analysis showed that LVEF<50%and the total score of myocardial ischemia>12 were independent risk factors of MACE within 3 y after PCI in AMI patients(P<0.05).Conclusion The parameters related to dual nuclide myocardial imaging can be taken as one of predictive indicators for MACE in AMI patients after PCI.