Relationship between left anterior descending mid-myocardial bridgeand atherosclerotic plaquedistribu-tion and its influence on plaque stability in patients with coronary atherosclerosis
Relationship between left anterior descending mid-myocardial bridgeand atherosclerotic plaquedistribu-tion and its influence on plaque stability in patients with coronary atherosclerosis
Objective To discuss the distribution and stability of atherosclerotic plaque(AP)in patients with left anterior descending mid-myocardial bridge(mid-LAD-MB).Methods The patients with mid-LAD-MB(n=139)confirmed by coronary CT angiography were chosen from Department of Radiology in the First Hospital of Zhangjiakou City from Jan.2022 to Jan.2023.The patients were divided into AP+MB group(n=54)and MB group(n=85),and after propensity score matching(PSM)baseline data,there were 39 cases in each group.At the same time,the patients with only AP were selected into AP group(n=39).The characteristics of MB and coronary imagines,AP quantitative indexesand their distribution were compared among the groups.The relationship between MB and AP were analyzed by usingSpearman correlation coefficient and Logistic regression analysis.Results After PSM,the degree of coronary compression was higher in MB+AP group than that in MB group(P＜0.05).The location and distance between AP and MB inlet in MB anterior segment were less,and AP liposome volume,length and load were higherof deep-embedded MBthan those of incomplete and superficial MB(P＜0.05).At distance of 60 mm to 80 mm from the left coronary sinus orifice,the number of AP was less in MB+AP group than that in AP group(0 and 10,P＜0.05).MB location was positively correlated to AP liposome volume(r=0.92,P＜0.05),number(r=0.70,P＜0.05),length(r=0.77,P＜0.05)and loading(r=0.93,P＜0.05).There was a strong correlation between MB location and AP liposome volume and loading(Ptrend＜0.05).Conclusion AP mostly distributes in MB anterior segment in patients with mid-LAD-MB,and deep-embedded MB or MB with deeper location will increase AP instability.
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