Objective To study the predictive value of detection of pericoronary adipose tissue(PCAT)to long-term prognosis in patients with acute coronary syndromes(ACS).Methods ACS patients(n=145)were chosen from the Second Hospital of Baoding City from Jan.2020 to Jan.2021 and they were followed up for 3 y.All patients were divided,according to occurrence of major adverse cardiovascular events(MACE)during follow-up period,into MACE group and non-MACE group.All patients were given PCAT detection.The predictive efficacy of PCAT detection to MACE incidence was analyzed.Results The indexes of body mass index(BMI),hypertension,3-vessel lesion and fat attenuation index(FAI)of PCAT had statistical difference between 2 groups(P<0.05).The results of Logistic regression analysis showed that 3-vessel lesion,FAIleft anterior descending branch(LAD-FAI),FAIofleft circumflex of coronary artery(LCX-FAI)and FAIof right coronary artery(RCA-FAI)were effective risk predictive factors for MACE in ACS patients(all P<0.05).The results of ROC curve analysis showed that LAD-FAI,LCX-FAI and RCA-FAI had some predictive value to MACE,and AUC was,respectively,0.927,0.951 and 0.986(95%CI:0.887~0.967,95%CI:0.922~0.981 and 95%CI:0.974~0.998,P<0.05),sensitivity was,respectively,74.6%,79.1%and 97.1%,and specificity was,respectively,94.8%,96.1%and 88.3%.Conclusion The detection of PCAT can predict the occurrence of MACE and has a higher value to long-term prognosis in ACS patients,which is worth clinical promoting.