Objective To discuss the predictive value of coronary artery plaque loading to relapsed major adverse cardiovascular events(MACE)in patients with acute myocardial infarction(AMI).Methods AMI patients(n=248)were retrospectively chosen from the First Affiliated Hospital of Xinjiang Medical University from Jan.2018 to Sept.2020.The patients were followed up for 3 y,and divided,according to MACE occurrence,into MACE group(n=56)and control group(n=192).The coronary artery plaque loading was detected by using coronary computed tomography angiography(CCTA)in all patients,and predictive value of coronary artery plaque loading to MACE was analyzed.Results Compared with control group,incidence of diabetes increased significantly(62.50％vs.46.35％,P=0.033),age increased significantly(70.68±11.79 vs.59.80±14.24,P＜0.001),coronary artery calcified plaque loading(％)increased significantly(21.79±2.31 vs.19.52±2.03,P＜0.001),coronary artery non-calcified plaque loading(％)increased significantly(21.56±3.63 vs.14.24±2.88,P＜0.001),and left ventricular ejection fraction(LVEF,％)decreased significantly(50.46±3.58 vs.52.84±3.59).The results of multi-factor Logistics regression analysis showed that coronary artery non-calcified plaque loading＞17.805％,coronary artery calcified plaque loading＞19.99％,age ≥ 80,LVEF＜50％and diabetes were independent risk factors(P＜0.05)for MACE relapse in AMI patients within 3 y.The coronary artery non-calcified plaque loading(AUC=0.934,95％CI:0.900～0.968,P＜0.001)and coronary artery calcified plaque loading(AUC=0.755,95％CI:0.687～0.824,P＜0.001)had a higher predictive value to MACE relapse.Conclusion The increased coronary artery plaque loading is an independent influence factor for MACE relapse and an effective index for predicting MACE in AMI patients.
维普
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