Clinical study on effects of external counterpulsation on cardiac function and quality of life in patients with heart failure with median ejection fraction
Clinical study on effects of external counterpulsation on cardiac function and quality of life in patients with heart failure with median ejection fraction
Objective To investigate the effect of external counterpulsation on cardiac function and quality of life in patients with heart failure with median ejection fraction.Methods A total of 80 cases of heart failure with General practice and cardiovascular medicine-median ejection fraction admitted to Zhabei Central Hospital,Jing'a District,Shanghai,from March 2022 to January 2023 were selected as the study objects.and randomly divided into an external counterpulsation group and a conventional drug group.The conventional drug group was given conventional drug treatment according to the《2018 Chinese Guidelines for the Diagnosis and Treatment of Heart Failure》.External counterpulsation treatment was selected based on conventional drugs in the external counterpulsation group.The clinical efficacy of the two groups of patients was compared,and the cardiac function indexes,NT-proBNP level,6-minute walking test distance,quality of life and cardiovascular adverse events of the two groups were compared before treatment,42 days,3 months,6 months and 12 months after treatment.Results The total effective rate of the external counterpulsation group was 95.00％,which was significantly higher than that of the conventional drug group(80％)(P＜0.05).At 3 months and 6 months after treatment,LVEF in the ECP group was significantly higher than that in the conventional drug group,LAD,LVDd,and LVDs were lower than that in the conventional drug group,and the 6-minute walking test distance was greater than that in the conventional drug group(P＜0.05).At 3 months,6 months after treatment,the serum level of NT-proBNP in the ECP group was significantly lower than that in the conventional drug group,the MLHF score was significantly lower than that in the conventional drug group,and the rate of rehospitalization for heart failure(15.00％vs.35.00％,P=0.039)was significantly lower than that in the conventional drug group(P＜0.05).Conclusions Extracorporeal counterpulsation is effective in HFmrEF patients and can significantly improve cardiac function.
关键词
射血分数中间值心力衰竭/体外反搏/临床疗效/心功能
Key words
Median ejection fraction heart failure/External counterpulsation/Clinical effect/Heart function
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