中国循证心血管医学杂志2024,Vol.16Issue(7) :785-788.DOI:10.3969/j.issn.1674-4055.2024.07.05

高龄高血压患者餐后低血压与血管生理参数及衰弱程度的相关性研究

Correlation among postprandial hypotension,vascular physiological parameters and asthenic degree in elderly patients with hypertension

贺琼逸 范兴满 方舟 王新宴 马晨越 王猛 张海涛
中国循证心血管医学杂志2024,Vol.16Issue(7) :785-788.DOI:10.3969/j.issn.1674-4055.2024.07.05

高龄高血压患者餐后低血压与血管生理参数及衰弱程度的相关性研究

Correlation among postprandial hypotension,vascular physiological parameters and asthenic degree in elderly patients with hypertension

贺琼逸 1范兴满 2方舟 3王新宴 3马晨越 4王猛 2张海涛1
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作者信息

  • 1. 100142 北京,空军军医大学空军特色医学中心心血管内科;230032 合肥,安徽医科大学第五临床医学院安徽医科大学空军临床学院心血管内科
  • 2. 075000 张家口,河北北方学院研究生院
  • 3. 100142 北京,空军军医大学空军特色医学中心心血管内科
  • 4. 230032 合肥,安徽医科大学第五临床医学院安徽医科大学空军临床学院心血管内科
  • 折叠

摘要

目的 探讨高龄高血压患者餐后低血压与相关血管生理参数以及衰弱程度之间的相关性.方法 选择空军特色医学中心89例平均年龄89岁的高龄高血压住院患者为研究对象,根据是否发生餐后低血压(PPH)的定义分为PPH组和非PPH组.描述不同组间的血管生理参数情况,并结合衰弱、自护能力量表进一步探讨餐后低血压与不同影响因素之间的关系.结果 研究表明,PPH组患者踝肱指数(ABI)显著低于非PPH组(1.10±0.13vs.1.17±0.13,P<0.05),PPH组Ⅲ~Ⅳ级眼底血管硬化患者明显多于非PPH组(34.7%vs.10.0%,P<0.05),而非PPH组衰弱患者明显多于PPH组(55.0%vs.32.7%,P<0.05).二元Logistic回归分析显示衰弱程度(OR=0.225,95%CI:0.072~0.709,P<0.05)、ABI(OR=0.001,95%CI:0.000~0.215,P<0.05)、眼底血管硬化程度(OR=4.904,95%CI:1.271~18.920,P<0.05)可显著影响PPH的发生.结论 高龄高血压患者餐后低血压与ABI、眼底血管硬化以及衰弱程度存在显著相关性.

Abstract

Objective To investigate the correlation among postprandial hypotension(PPH),vascular physiological parameters and asthenic degree in elderly patients with hypertension.Methods The very old patients with hypertension(averagely aged 89 years old,n=89)were chosen from Air Force Specialty Medical Center of Chinese PLA Air Force Medical University.The patients were divided,according to whether they had PPH or not,into PPH group and non-PPH group.The vascular physical parameters were described in all groups.The relationship among PPH and different influence factors was analyzed based on scales of asthenia and self-care ability.Results The level of ankle-brachial index(ABI)was significantly lower(1.10±0.13 vs.1.17±0.13,P<0.05),and cases of fundus angiosclerosis were significantly more(34.7%vs.10.0%,P<0.05)in PPH group than those in non-PPH group,while asthenic patients(55.0%vs.32.7%,P<0.05)were more in non-PPH group than those in non-PPH group.The results of binary Logistic regression analysis showed that asthenic degree(OR=0.225,95%CI:0.072~0.709,P<0.05),ABI(OR=0.001,95%CI:0.000~0.215,P<0.05)and severity of fundus angiosclerosis(OR=4.904,95%CI:1.271~18.920,P<0.05)had significant influence on PPH occurrence.Conclusion PPH,ABI and fundus angiosclerosis had significant correlation with asthenic degree in very old patients with hypertension.

关键词

高血压/高龄/餐后低血压/血管/衰弱

Key words

Hypertension/Agedness/Postprandial hypotension(PPH)/Blood vessel/Asthenia

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出版年

2024
中国循证心血管医学杂志
中国人民解放军北京军区总医院

中国循证心血管医学杂志

CSTPCD
影响因子:1.272
ISSN:1674-4055
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