中国循证心血管医学杂志2024,Vol.16Issue(8) :983-985.DOI:10.3969/j.issn.1674-4055.2024.08.17

终末期肝病模型-Ⅺ评分对急性心肌梗死冠状动脉支架植入术后患者预后的预测价值

Predictive value of scores of model for end-stage liver disease-Ⅺ to prognosis in patients with acute my-ocardial infarction after intracoronary stent implantation

公方娜 单鸿伟 廉明 宝璐尔 阿拉腾宝力德 关宏
中国循证心血管医学杂志2024,Vol.16Issue(8) :983-985.DOI:10.3969/j.issn.1674-4055.2024.08.17

终末期肝病模型-Ⅺ评分对急性心肌梗死冠状动脉支架植入术后患者预后的预测价值

Predictive value of scores of model for end-stage liver disease-Ⅺ to prognosis in patients with acute my-ocardial infarction after intracoronary stent implantation

公方娜 1单鸿伟 1廉明 1宝璐尔 2阿拉腾宝力德 2关宏2
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作者信息

  • 1. 010050呼和浩特,内蒙古医科大学附属医院急诊内科
  • 2. 010050 呼和浩特,内蒙古医科大学附属医院心内科
  • 折叠

摘要

目的 探讨终末期肝病模型-Ⅺ(MELD-Ⅺ)评分对急性心肌梗死患者冠状动脉支架植入术后的预后的预测价值.方法 回顾性收集2021年1月至2022年12月于内蒙古医科大学附属医院收治的急性心肌梗死患者226例,根据入院时MELD-Ⅺ评分,将患者分为高MELD-Ⅺ评分组和低MELD-Ⅺ评分组,每组各113例.比较两组患者近、远期预后.结果 与低MELD-Ⅺ评分组比较,高MELD-Ⅺ评分组患者左室射血分数(LVEF)显著降低[(51.67±7.91)%vs.(60.91±5.91)%],(P<0.001);N末端脑钠肽前体(NT-proBNP)显著增高(822.87±462.38)vs.(701.84±338.21)ng/L,(P=0.026).与低MELD-Ⅺ评分组比较,高MELD-Ⅺ评分组患者不良结局事件的发生率显著增高(16.81%vs.6.19%,P=0.012).MELD-Ⅺ评分对急性心肌梗死冠状动脉支架植入术后不良结局事件具有一定的预测价值,曲线下面积为0.732,95%CI:0.671~0.798,(P<0.001).结论 MELD-Ⅺ对于预测急性心肌梗死患者预后具有一定的参考价值.

Abstract

Objective To discuss the predictive value of scores of model for end-stage liver disease-Ⅺ(MELD-Ⅺ)to prognosis in patients with acute myocardial infarction(AMI)after intracoronary stent implantation.Methods AMI patients(n=226)were retrospectively chosen from Affiliated Hospital of Inner Mongolia Medical University from Jan.2021 to Dec.2022.According to MELD-Ⅺ scores at admission time,the patients were divided into high MELD-Ⅺ score group and low MELD-Ⅺ score group(each n=113).The short-term and long-term prognoses were compared between 2 groups.Results Compared with low MELD-Ⅺ score group,left ventricular ejection fraction(LVEF)decreased significantly[(51.67±7.91)%vs.(60.91±5.91)%],(P<0.001),and N-terminal pro-brain natriuretic peptide(NT-proBNP)increased significantly(822.87±462.38)ng/L vs.(701.84±338.21)ng/L,(P=0.026)in high MELD-Ⅺ score group.The incidence rates of adverse outcome events increased significantly in high MELD-Ⅺ score group compared with low MELD-Ⅺ score group(16.81%vs.6.19%,P=0.012).MELD-Ⅺ score had some predictive value to adverse outcome events in AMI patients after intracoronary stent implantation(AUC=0.732,95%CI:0.671~0.798),(P<0.001).Conclusion MELD-Ⅺ has some reference value in predicting prognosis in AMI patients.

关键词

终末期肝病模型-Ⅺ/急性心肌梗死/心脏功能/预后/冠状动脉支架植入术

Key words

Model for end-stage liver disease-Ⅺ/Acute myocardial infarction/Heart function/Prognosis/Intracoronary stent implantation

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基金项目

内蒙古自治区自然科学基金项目(2023MS08018)

内蒙古自治区卫生健康科技计划基金项目(202201243)

出版年

2024
中国循证心血管医学杂志
中国人民解放军北京军区总医院

中国循证心血管医学杂志

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影响因子:1.272
ISSN:1674-4055
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