中国循证心血管医学杂志2024,Vol.16Issue(12) :1483-1486.DOI:10.3969/j.issn.1674-4055.2024.12.16

非瓣膜性心房颤动住院患者抗凝治疗的临床现状分析

Clinical analysis of anticoagulation therapy in inpatients with nonvalvular atrial fibrillation

严翼 徐锋
中国循证心血管医学杂志2024,Vol.16Issue(12) :1483-1486.DOI:10.3969/j.issn.1674-4055.2024.12.16

非瓣膜性心房颤动住院患者抗凝治疗的临床现状分析

Clinical analysis of anticoagulation therapy in inpatients with nonvalvular atrial fibrillation

严翼 1徐锋1
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作者信息

  • 1. 214400 江阴,江阴市人民医院心血管内科
  • 折叠

摘要

目的 心房颤动是临床常见的心律失常之一,患病率较高且易导致脑卒中,抗凝治疗是预防心房颤动相关性卒中的核心策略.方法 本研究采用回顾性分析,收集2022年1月至2022年12月于江阴市人民医院心血管内科住院治疗的非瓣膜性心房颤动患者,记录患者性别、年龄、心房颤动类型、合并症、卒中风险评分(CHA2DS2-VASc评分)、出血风险评分(HAS-BLED评分)、相关辅助检查及治疗方案等.结果 本研究共纳入非瓣膜性心房颤动患者304例,平均年龄(70.67±11.18)岁,男女性别比1.14.伴随疾病和心血管危险因素中,合并高血压189例(62.17%),冠状动脉粥样硬化性心脏病156例(51.32%),心力衰竭123例(40.46%),永久性心房颤动患者冠状动脉粥样硬化性心脏病(冠心病)和心力衰竭的患病率远高于阵发性心房颤动患者(P<0.001).不同心房颤动类型患者在抗凝治疗率上无明显差别(P=0.287),未抗凝治疗的患者,其平均年龄比抗凝治疗患者大(P<0.05).结论 本院就诊的非瓣膜性心房颤动患者以老年人为主.高血压、心力衰竭、冠心病为心房颤动的主要伴随疾病.选择新型口服抗凝药治疗,总体抗凝比例较高,但对于年龄大,有出血史的心房颤动患者,需进一步规范抗凝治疗.

Abstract

Objective Atrial fibrillation is a common arrhythmia in clinical practice,with a high prevalence rate and easy to lead to stroke.Anticoagulation therapy is the core strategy to prevent atrial fibrillation related stroke.Methods A retrospective case analysis was used to collect patients with nonvalvular atrial fibrillation who were admitted to the Cardiovascular Department of Jiangyin People's Hospital from January 2022 to December 2022.The patient's gender,age,type of atrial fibrillation,comorbidities,stroke risk score (CHA2DS2-VASc score),bleeding risk score (HAS-BLED score),related auxiliary examination and treatment plan were recorded.Results A total of 304 patients with nonvalvular atrial fibrillation were included in this study,with an average age of (70.67±11.18) years and a sex ratio of 1.14.Among the concomitant diseases and cardiovascular risk factors,189 cases (62.17%) were complicated with hypertension,156 cases (51.32%) with coronary heart disease,and 123 cases (40.46%) with heart failure.The prevalence of coronary heart disease and heart failure in patients with permanent atrial fibrillation was much higher than that in patients with paroxysmal atrial fibrillation(P<0.001).There was no significant difference in the rate of anticoagulant treatment among patients with different types of atrial fibrillation(P=0.287).The mean age of patients without anticoagulant treatment was older than that of patients with anticoagulant treatment(P<0.05).Conclusion The majority of patients with nonvalvular atrial fibrillation in our hospital are elderly.Hypertension,heart failure and coronary heart disease are the main concomitant diseases of atrial fibrillation.Most patients chose new oral anticoagulant therapy,and the overall anticoagulant ratio was relatively high,but the anticoagulant therapy was still further improved for atrial fibrillation patients with old age and bleeding history.

关键词

心房颤动/心血管疾病/脑卒中/抗凝治疗/新型口服抗凝药

Key words

Atrial fibrillation/Cardiovascular diseases/Stroke/Anticoagulant therapy/New oral anticoagulants

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出版年

2024
中国循证心血管医学杂志
中国人民解放军北京军区总医院

中国循证心血管医学杂志

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影响因子:1.272
ISSN:1674-4055
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