Objective To discuss the predictive value of systemic immune inflammation index (SII) to long-term major adverse cardiovascular events (MACE) in patients with stable coronary heart disease (CHD).Methods The patients with stable CHD (n=473) were chosen,and according to MACE occurrence status,divided into MACE group (n=113) and control group (n=360) in Central Hospital of Xianyang City from Jan.2017 to Dec.2018.The differences in clinical features and SII were compared between 2 groups.The predictive value of SII to MACE and risk factors for long-term MACE were analyzed.Results The levels of age increased (67.51±11.76 vs.61.48±12.05,P＜0.001) and left ventricular ejection fraction (LVEF,49.70±6.18％ vs.52.60±6.42％,P＜0.001) decreased,percentage of coronary multi-vessel lesions increased (65.49％ vs.40.28％,P＜0.001),mean severity of coronary artery stenosis increased (81.20±10.19％ vs.72.19±10.61％,P＜0.001),SII increased (902.37±312.58 vs.645.87±221.04,P＜0.001),and percentage of patients with poor medication compliance increased (39.82％ vs.22.22％,P＜0.001) in MACE group compared with control group.SII had a higher value to long-term MACE with AUC=0.731 (95％CI:0.678～0.792) in patients with stable CHD.SII was significantly correlated to LVEF (r=-0.241,P=0.002),and positively correlated to severity of coronary artery stenosis (r=0.304,P＜0.001).When SII≥692,it was a risk factor for MACE occurrence (P=0.001,RR=2.238,95％CI:1.032～4.585).Conclusion SII can be taken as a predictive index for MACE occurrence in patients with stable CHD.For patients with increased SII,monitoring should be strengthened to reduce MACE occurrence.
维普
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