首页|目标试验模拟研究辅助实施工具CERBOT简介与应用

目标试验模拟研究辅助实施工具CERBOT简介与应用

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因果推断的快速发展正在引起众多学科领域研究的"范式革命"."目标试验模拟"被认为是一种极具前景的观察性真实世界研究框架,已经受到国内外卫生领域学者和监管部门的广泛关注.本文旨在概述目标试验模拟研究进展的基础上,介绍目标试验模拟研究在线辅助实施工具CERBOT的基本情况,并通过一项实例对其操作过程进行说明,以期帮助国内研究人员开展目标试验模拟研究,并为最终促进国内医疗领域真实世界研究质量和医疗服务水平产生积极影响.
Introduction and application of an auxiliary implementation tool(CERBOT)for target trial emulation study
The rapid advancement of causal inference is driving a paradigm shift across various disciplines."Target trial emulation"has emerged as an exceptionally promising framework for observational real-world studies,attracting substantial attention from medical scholars and regulatory agencies worldwide.This article aims to provide an introduction to CERBOT,an online tool that assists in implementing target trial emulation studies,while highlighting the advancements in this domain.Additionally,the article provides an illustrative example to elucidate the operational process of CERBOT.The objectives are to support domestic researchers in conducting target trial emulation studies and enhance the quality of real-world studies in the domestic medical field,as well as improve the medical service level in clinical practice.

Target trialCausal inferenceComparative effectiveness researchReal-world data

卢存存、柯立鑫、王子怡、陈子佳、王志飞

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中国中医科学院中医临床基础医学研究所(北京 100700)

格罗宁根大学医学中心儿科学实验室(荷兰格罗宁根9713GZ)

兰州大学公共卫生学院循证社会科学研究中心(兰州 730000)

目标试验 因果推断 比较效果研究 真实世界数据

中国中医科学院科技创新工程项目

CI2021A00702

2024

中国循证医学杂志
四川大学

中国循证医学杂志

CSTPCD北大核心
影响因子:1.761
ISSN:1672-2531
年,卷(期):2024.24(2)
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