Comprehensive intervention for sarcopenia among older adults:an evidence-based clinical practice guideline
Sarcopenia,characterized by the progressive loss of muscle mass and function,predominantly afflicts older adults.This condition is a notable risk factor for functional impairments,increased incidence of falls and fractures,and can escalate to mortality.Timely intervention is crucial to mitigate disability and minimize complications during hospitalization.The development of these guidelines adhered to an internationally recognized standard protocol.This involved framing clinical queries,pinpointing key outcomes,systematically gathering evidence,and appraising this evidence through the Grading of Recommendations,Assessment,Development,and Evaluation(GRADE)framework.Subsequently,a consortium of experts convened to deliberate over the evidence,culminating in the formulation of these recommendations.