Selective non-reporting and publication bias of study results threaten the validity of systematic reviews and meta-analyses,thus affect clinical decision making.There are no rigorous methods to evaluate the risk of bias in network meta-analyses currently.This paper introduces the main contents of ROB-MEN(risk of bias due to missing evidence in network meta-analysis),including tables of the tool,operation process and signal questions.The pairwise comparisons table and the ROB-MEN table are the tool's core.The ROB-MEN tool can be applied to very large and complex networks including lots of interventions to avoid time-consuming and labor-intensive process,and it has the advantages of clear logic,complete details and good applicability.It is the first tool used to evaluate the risk of bias due to missing evidence in network meta-analysis and is useful to researchers,thus being worth popularizing and applying.
关键词
证据缺失偏倚/发表偏倚/偏倚风险/系统评价/网状Meta分析/两两比较
Key words
Bias due to missing evidence/Publication bias/Risk of bias/Systematic review/Network meta-analysis/Pairwise comparison
维普
万方数据