A Chinese introduction to risk of bias due to missing evidence in network meta-analysis(ROB-MEN)
Selective non-reporting and publication bias of study results threaten the validity of systematic reviews and meta-analyses,thus affect clinical decision making.There are no rigorous methods to evaluate the risk of bias in network meta-analyses currently.This paper introduces the main contents of ROB-MEN(risk of bias due to missing evidence in network meta-analysis),including tables of the tool,operation process and signal questions.The pairwise comparisons table and the ROB-MEN table are the tool's core.The ROB-MEN tool can be applied to very large and complex networks including lots of interventions to avoid time-consuming and labor-intensive process,and it has the advantages of clear logic,complete details and good applicability.It is the first tool used to evaluate the risk of bias due to missing evidence in network meta-analysis and is useful to researchers,thus being worth popularizing and applying.
Bias due to missing evidencePublication biasRisk of biasSystematic reviewNetwork meta-analysisPairwise comparison
万方数据
维普
