Comparison of different ORC uses in VATS for lung cancer resection based on real-world data
Objective To evaluate the safety,efficacy,and cost-effectiveness of different uses of oxidized regenerated cellulose(ORC)in video-assisted thoracoscopic surgery(VATS)for lung cancer resection to provide a reference for the selection,clinical use,and rational utilization of absorbable hemostatic materials.Methods A retrospective analysis of relevant data from inpatients who underwent VATS for lung cancer resection at a tertiary hospital from July 2019 to January 2020 and from July 2020 to December 2020 was conducted.Patients were divided into two groups based on the use of ORC:1)combined use group(ORC and collagen sponge)and 2)sole-use group(ORC).Safety,efficacy,and economic outcome indicators were compared between the two groups.Results The main analysis included a total of 904 patients,with 466 in the combined use group and 438 in the sole-use group.Compared to the combined use group,the sole-use group had a significantly longer hospital stay,used fewer hemostatic drugs,had a lower average cost of hemostatic materials,and a lower median total hospitalization cost(P＜0.05).No statistically significant difference was found between the two groups in terms of intraoperative blood loss volume,massive blood loss rate,perioperative transfusion rate,reoperation rate,postoperative 48-hour drainage volume,bloody drainage fluid rate,or postoperative laboratory test indicators.Conclusion There was no significant difference in the safety or efficacy of VATS for lung cancer resection between the sole use of ORC and the combined use of ORC,but the sole use of ORC was associated with a lower cost of hemostatic materials and a lower total hospitalization cost.The sole use of hemostatic gauze in VATS for lung cancer resection may be a more cost-effective choice.
万方数据
维普
