Structured grading and evaluation of clinical questions in clinical practice guidelines
In the process of guideline development and construction of clinical questions,it is necessary to guide clinicians to propose clinical problems into PICO(population,intervention,control,outcome)structured clinical questions.However,there are still unclear criteria to define and judge the appropriateness of the width of the PICO elements of a clinical question.Either too wide or too narrow can make the PICO question unsuitable to be a question for clinical practice guidelines to answer.We graded the clinical questions to be eight grades(3,2,1,0,-1,-2,-3,mixed)according to the number of the PIC elements,which obviously needed to be adjusted to evaluate applicability of the appropriateness of the width of the clinical questions.Our work can provide methodological references for clinicians and guideline developers.
Clinical questionPICOClinical practice guidelineMethodology